Targeting the perinatal diet to modulate the gut microbiota increases dietary variety and prebiotic and probiotic food intakes: results from a randomised controlled trial

被引：12

作者：

Dawson, Samantha L. ^{[1
,2
]}

Mohebbi, Mohammadreza ^{[3
]}

Craig, Jeffrey M. ^{[2
,4
]}

Dawson, Phillip ^{[5
]}

Clarke, Gerard ^{[6
,7
,8
]}

Tang, Mimi L. K. ^{[9
,10
]}

Jacka, Felice N. ^{[1
,11
,12
,13
]}

机构：

[1] Deakin Univ, IiMPACT Inst Mental & Phys Hlth & Clin Translat, Food & Mood Ctr, Hlth Educ & Res Bldg HERB,Level 3,POB 281, Geelong, Vic 3220, Australia

[2] Royal Childrens Hosp, Royal Childrens Hosp, Environm & Genet Epidemiol Res, Parkville, Vic, Australia

[3] Deakin Univ, Fac Hlth, Biostat Unit, Geelong, Vic, Australia

[4] Deakin Univ, Sch Med, Geelong, Vic, Australia

[5] Deakin Univ, Ctr Res Assessment & Digital Learning, Melbourne, Australia

[6] Univ Coll Cork, Dept Psychiat & Neurobehav Sci, Cork, Ireland

[7] Univ Coll Cork, APC Microbiome Ireland, Cork, Ireland

[8] Univ Coll Cork, INFANT Res Ctr, Cork, Ireland

[9] Royal Childrens Hosp, Murdoch Childrens Res Inst, Allergy Immunol Res, Parkville, Vic, Australia

[10] Univ Melbourne, Dept Paediat, Parkville, Vic, Australia

[11] Royal Childrens Hosp, Murdoch Childrens Res Inst, Ctr Adolescent Hlth, Parkville, Vic, Australia

[12] Black Dog Inst, Randwick, NSW, Australia

[13] James Cook Univ, Townsville, Qld, Australia

来源：

PUBLIC HEALTH NUTRITION | 2021年 / 24卷 / 05期

关键词：

Pregnancy; Diet quality; Gut microbiota; Behaviour change intervention; Randomised controlled trial; COMMON AUSTRALIAN VEGETABLES; PREGNANT-WOMEN; PHYSICAL-ACTIVITY; MATERNAL DIET; METAANALYSIS; HEALTH; INTERVENTIONS; GUIDELINES; BEHAVIORS; NUTRITION;

D O I：

10.1017/S1368980020003511

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Objective: To evaluate the hypothesis that a perinatal educational dietary intervention focused on 'eating for the gut microbiota' improves diet quality of pregnant women pre- and postnatally. Design: The Healthy Parents, Healthy Kids study is a prospectively registered randomised controlled trial designed to evaluate the efficacy of a dietary intervention in altering the maternal and infant gut microbiota and improving perinatal diet quality. Eligible pregnant women were randomised to receive dietary advice from their healthcare provider or to additionally receive a three session dietary intervention. Dietary data were collected at gestation weeks 26, 31, 36 and postnatal week 4. Outcome measures were diet quality, dietary variety, prebiotic and probiotic food intakes, energy, fibre, saturated fat and discretionary food intakes. Between-group differential changes from baseline before and after birth in these dietary measures were assessed using generalised estimating equations. Setting: Melbourne, Australia. Participants: Healthy pregnant women from gestation week 26. Results: Forty-five women were randomised (twenty-two control, twenty-three intervention). Compared with the control group, the intervention group improved diet quality prior to birth (5 center dot 66 (95 % CI 1 center dot 65, 9 center dot 67), Cohen's d: 0 center dot 82 (se 0 center dot 33)). The intervention improved dietary variety (1 center dot 05 (95 % CI 0 center dot 17, 1 center dot 94), d: 0 center dot 66 (se 0 center dot 32)) and increased intakes of prebiotic (0 center dot 8 (95 % CI 0 center dot 27, 1 center dot 33), d: 0 center dot 91 (se 0 center dot 33)) and probiotic foods (1 center dot 05 (95 % CI 0 center dot 57, 1 center dot 53), d: 1 center dot 3(se 0 center dot 35)) over the whole study period compared with the control group. Conclusion: A dietary intervention focused on 'eating for the gut microbiota' can improve aspects of perinatal diet quality during and after pregnancy.

引用

页码：1129 / 1141

页数：13

共 58 条

[1] Postbiotics: An evolving term within the functional foods field [J].