Comparison of predictability of epileptic seizures by a linear and a nonlinear method

被引:38
作者
McSharry, PE
Smith, LA
Tarassenko, L
机构
[1] Univ Oxford, Dept Engn Sci, Oxford OX1 3PJ, England
[2] Univ Oxford, Inst Math, Oxford OX1 3LB, England
[3] Univ London London Sch Econ & Polit Sci, Ctr Anal Time Series, London WC2A 2AE, England
关键词
epilepsy; nonlinear; null hypothesis; prediction; surrogates; time series;
D O I
10.1109/TBME.2003.810688
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The performance of traditional linear (variance based) methods for the identification and prediction of epileptic seizures are contrasted with "modern" methods from nonlinear time series analysis. We note several flaws of design in demonstrations claiming to establish the efficacy of nonlinear techniques;. in particular, we examine published evidence for precursor identification. We perform null hypothesis tests using relevant surrogate data to demonstrate that decreases in the correlation density prior to and during seizure may simply reflect increases in the variance.
引用
收藏
页码:628 / 633
页数:6
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