Colorectal cancer prognosis twenty years later

被引：31

作者：

Bujanda, Luis ^{[1
]}

Sarasqueta, Cristina ^{[2
]}

Hijona, Elisabeth ^{[1
]}

Hijona, Lander ^{[1
]}

Cosme, Angel ^{[1
]}

Gil, Ines ^{[1
]}

Luis Elorza, Jose ^{[3
]}

Asensio, Jose I. ^{[3
]}

Larburu, Santiago ^{[3
]}

Enriquez-Navascues, Jose M. ^{[3
]}

Jover, Rodrigo ^{[4
]}

Balaguer, Francesc ^{[5
]}

Llor, Xavier ^{[6
]}

Bessa, Xavier ^{[7
]}

Andreu, Montserrat ^{[7
]}

Paya, Artemio ^{[5
]}

Castells, Antoni ^{[4
]}

机构：

[1] Univ Basque Country, Dept Gastroenterol, CIBEREHD, Donostia Hosp, San Sebastian 20014, Spain

[2] CIBERESP, Donostia Hosp, Dept Epidemiol, San Sebastian 20014, Spain

[3] Donostia Hosp, Dept Surg, San Sebastian 20014, Spain

[4] Gen Hosp, Dept Gastroenterol, Alicante 03010, Spain

[5] IDIBAPS, CIBEREHD, Clin Hosp, Dept Gastroenterol, Barcelona 08036, Spain

[6] Univ Illinois, Digest Dis & Nutr Sec, Chicago, IL 60607 USA

[7] Hosp del Mar, Dept Gastroenterol, Barcelona 08003, Spain

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2010年 / 16卷 / 07期

关键词：

Colon cancer; Prognosis; Survival; Chemotherapy; Surgery; REVISED BETHESDA GUIDELINES; ADJUVANT THERAPY; ACCEPTABLE MORBIDITY; 30-DAY MORTALITY; COLON-CANCER; SURGERY; IDENTIFICATION; POPULATION;

D O I：

10.3748/wjg.v16.i7.862

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

AIM: To evaluate changes in colorectal cancer (CRC) survival over the last 20 years. METHODS: We compared two groups of consecutive CRC patients that were prospectively recruited: Group I included 1990 patients diagnosed between 1980 and 1994. Group H included 871 patients diagnosed in 2001. RESULTS: The average follow up time was 21 mo (1-229) for Group I and 50 mo (1-73.4) for Group U. Overall median survival was significantly longer in Group II than in Group 1 (73 mo vs 25 mo, P < 0.001) and the difference was significant for all tumor stages. Post surgical mortality was 8% for Group I and 2% for Group H (P < 0.001). Only 17% of Group I patients received chemotherapy compared with 50% of Group U patients (P < 0.001). CONCLUSION: Survival in colorectal cancer patients has doubled over the past 20 years. This increase seems to be partly due to the generalization in the administration of chemotherapy and to the decrease of post surgical mortality. (C) 2010 Baishideng. All rights reserved.

引用

页码：862 / 867

页数：6

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