18F-FDG and 68Ga-FAPI PET/CT in the Evaluation of Ground-Glass Opacity Nodule

被引：12

作者：

Chen, Haojun ^{[1
,2
]}

Pang, Yizhen ^{[1
,2
]}

Meng, Tinghua ^{[1
,2
]}

Yu, Xiuyi ^{[3
]}

Sun, Long ^{[1
,2
]}

机构：

[1] Xiamen Univ, Xiamen Canc Ctr, Affiliated Hosp 1, Dept Nucl Med, Xiamen, Peoples R China

[2] Xiamen Univ, Xiamen Canc Ctr, Affiliated Hosp 1, Minnan PET Ctr, Xiamen, Peoples R China

[3] Xiamen Univ, Xiamen Canc Ctr, Affiliated Hosp 1, Dept Thorac Surg, Xiamen, Peoples R China

来源：

CLINICAL NUCLEAR MEDICINE | 2021年 / 46卷 / 05期

关键词：

F-18-FDG; Ga-68-FAPI; ground-glass opacity; low-dose CT; PET/CT; ACCUMULATION;

D O I：

10.1097/RLU.0000000000003600

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A 50-year-old woman with a newly detected pulmonary ground-glass opacity (GGO) nodule underwent PET/CT to determine the likelihood of malignancy. This patient was enrolled in the prospective study (NCT04588064) to determine the effectiveness of F-18-FDG and Ga-68-FAPI PET/CT for characterization of the GGO nodule. On PET/CT images, minimal F-18-FDG uptake but intense Ga-68-FAPI uptake was observed in this GGO nodule. This patient subsequently underwent video-assisted thoracoscopic surgery, and postoperative pathological examination confirmed the diagnosis of invasive adenocarcinoma. This case presented an example where Ga-68-FAPI PET/CT showed higher tracer uptake than F-18-FDG in the malignant GGO nodule.

引用

页码：424 / 426

页数：3

共 10 条

[1] Usefulness of [68Ga]Ga-DOTA-FAPI-04 PET/CT in patients presenting with inconclusive [18F]FDG PET/CT findings
Chen, Haojun
Zhao, Liang
Ruan, Dan
Pang, Yizhen
Hao, Bing
Dai, Yaqing
Wu, Xiurong
Guo, Wei
Fan, Chunlei
Wu, Jingxun
Huang, Weipeng
Lin, Qin
Sun, Long
Wu, Hua
[J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2021, 48 (01) : 73 - 86
[2] [18F]FDG and[68Ga]Ga-DOTA-FAPI-04 PET/CT in the evaluation of tuberculous lesions
Hao, Bing
Wu, Xiurong
Pang, Yizhen
Sun, Long
Wu, Hua
Huang, Weipeng
Chen, Haojun
[J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2021, 48 (02) : 651 - 652
[3] PET imaging in patients with bronchiolo alveolar cell carcinoma
Heyneman, LE
Patz, EF
[J]. LUNG CANCER, 2002, 38 (03) : 261 - 266
[4] Higashi K, 2001, J NUCL MED, V42, P1489
[5] Management of stage I and II nonsmall cell lung cancer
McDonald, Fiona
De Waele, Michele
Hendriks, Lizza E. L.
Faivre-Finn, Corinne
Dingemans, Anne-Marie C.
Van Schil, Paul E.
[J]. EUROPEAN RESPIRATORY JOURNAL, 2017, 49 (01)
[6] Ground glass opacities management in the lung cancer screening era
Migliore, Marcello
Fornito, Mariaconcetta
Palazzolo, Manuela
Criscione, Alessandra
Gangemi, Mariapia
Borrata, Francesco
Vigneri, Paolo
Nardini, Marco
Dunning, Joel
[J]. ANNALS OF TRANSLATIONAL MEDICINE, 2018, 6 (05)
[7] Elevated 68Ga-FAPI Accumulation in a Recurrent Angiomyolipoma
Qin, Chunxia
Gai, Yongkang
Liu, Qingyao
Shao, Fuqiang
Lan, Xiaoli
[J]. CLINICAL NUCLEAR MEDICINE, 2020, 45 (12) : 1034 - 1035
[8] Disentangling inflammatory from fibrotic disease activity by fibroblast activation protein imaging
Schmidkonz, Christian
Rauber, Simon
Atzinger, Armin
Agarwal, Rahul
Goetz, Theresa Ida
Soare, Alina
Cordes, Michael
Prante, Olaf
Bergmann, Christina
Kleyer, Arnd
Ritt, Philipp
Maschauer, Simone
Hennig, Peter
Toms, Johannes
Koehner, Markus
Manger, Bernhard
Stone, John H.
Haberkorn, Uwe
Baeuerle, Tobias
Distler, Joerg H. W.
Agaimy, Abbas
Kuwert, Torsten
Schett, Georg
Ramming, Andreas
[J]. ANNALS OF THE RHEUMATIC DISEASES, 2020, 79 (11) : 1485 - 1491
[9] Adenocarcinoma with BAC Features Presented as the Nonsolid Nodule Is Prone to Be False-Negative on 18F-FDG PET/CT
Wu, Hu-bing
Wang, Lijuan
Wang, Quan-shi
Han, Yan-jian
Li, Hong-sheng
Zhou, Wen-lan
Tian, Ying
[J]. BIOMED RESEARCH INTERNATIONAL, 2015, 2015
[10] 68Ga-FAPI-04 Accumulation in Myocardial Infarction in a Patient With Neuroendocrine Carcinoma
Zhu, Wenjia
Guo, Fan
Wang, Yawen
Ding, Haiyan
Huo, Li
[J]. CLINICAL NUCLEAR MEDICINE, 2020, 45 (12) : 1020 - 1022

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