Membrane-free microfiltration by asymmetric inertial migration

被引:119
作者
Seo, Jeonggi [1 ]
Lean, Meng H. [1 ]
Kole, Ashutosh [1 ]
机构
[1] Xerox Corp, Palo Alto Res Ctr, Palo Alto, CA 94304 USA
关键词
D O I
10.1063/1.2756272
中图分类号
O59 [应用物理学];
学科分类号
摘要
Membrane-free microfiltration by asymmetric inertial migration is studied and evidence of the filtration capability is presented. Centrifugal force induced by flow in spiral channel geometry modifies the lateral symmetry of straight-channel tubular pinch equilibrium resulting in a focused particle band nearer to the inner sidewall. Bifurcated outlets separately collect the concentrated particle band and remaining effluent. The spiral continuous flow filtration relies solely on internal fluidic shear characteristics, eliminating the need for membrane filters or external force fields. This device has the desirable combinations of high throughput and low cost, making it inherently suited for preparative filtration in the range of micro- to macroscale applications. (C) 2007 American Institute of Physics.
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页数:3
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