Cobalt-catalysed transfer hydrogenation of quinolines and related heterocycles using formic acid under mild conditions

被引:45
作者
Cabrero-Antonino, Jose R. [1 ]
Adam, Rosa [1 ]
Junge, Kathrin [1 ]
Jackstell, Ralf [1 ]
Beller, Matthias [1 ]
机构
[1] Univ Rostock, Leibniz Inst Katalyse eV, Albert Einstein Str 29a, D-18059 Rostock, Germany
关键词
ASYMMETRIC TRANSFER HYDROGENATION; N-HETEROCYCLES; STORAGE MATERIAL; WATER; DEHYDROGENATION; EFFICIENT; KETONES; HETEROARENES; COMPLEXES; NITRILES;
D O I
10.1039/c7cy00437k
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Herein, we report the first example of homogeneous non-noble metal-catalyzed transfer hydrogenation of N-heteroarenes. The combination of Co(BF4)(2)center dot 6H(2)O with tris.2-(diphenylphosphino)phenyl)phosphine L1 is able to selectively reduce quinolines in the presence of other sensitive functional groups, under mild conditions, using formic acid as a hydrogen source.
引用
收藏
页码:1981 / 1985
页数:5
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