RNA bulges as a target for selective cleavage by metal ions and organic compounds

被引：0
|
作者：
Kuznetsova, I. L. [1 ]
Zenkova, M. A. [1 ]
Vlassov, V. V. [1 ]
机构：
[1] Russian Acad Sci, Siberian Branch, Inst Chem Biol & Fundamental Med, Novosibirsk 630090, Russia
来源：
USPEKHI KHIMII | 2007年 / 76卷 / 03期
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中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The results of studies of the structure of RNA bulges are given. Cleavage of the phosphodiester bonds located in the bulges of RNA is considered. The attention is focused on the factors influencing the efficiency of this cleavage. The state-of-the-art of the problem of targeted RNA cleavage induced by various reagents is discussed.
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页码：305 / 316
页数：12
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