Functional MRI of language-related activation in left frontal schizencephaly

被引:10
作者
Spreer, J
Dietz, M
Raab, P
Arnold, S
Klisch, J
Lanfermann, H
机构
[1] Univ Freiburg, Dept Neuroradiol, Freiburg, Germany
[2] Univ Frankfurt, Dept Neurol, D-6000 Frankfurt, Germany
[3] Univ Frankfurt, Dept Neuroradiol, D-6000 Frankfurt, Germany
关键词
functional magnetic resonance imaging; schizencephaly; language; cortical dysplasia; blood oxygen level dependent (BOLD);
D O I
10.1097/00004728-200009000-00012
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Brain activation associated with covert verb generation was studied in a right-handed patient with an asymptomatic left frontal schizencephaly by functional magnetic resonance imaging. Activation of the dysplastic neuronal tissue lining the cleft and the adjacent cortex was found. indicating participation of the malformed region in physiologic cerebral functions. This finding may have clinical impact in patients with medically intractable seizures due to malformations of the cortical development prior to epilepsy surgery.
引用
收藏
页码:732 / 734
页数:3
相关论文
共 10 条
  • [1] BARKOVICH AJ, 1990, PEDIAT NEUROIMAGING, P99
  • [2] Language dominance determined by whole brain functional MRI in patients with brain lesions
    Benson, RR
    FitzGerald, DB
    LeSueur, LL
    Kennedy, DN
    Kwong, KK
    Buchbinder, BR
    Davis, TL
    Weisskoff, RM
    Talavage, TM
    Logan, WJ
    Cosgrove, GR
    Belliveau, JW
    Rosen, BR
    [J]. NEUROLOGY, 1999, 52 (04) : 798 - 809
  • [3] CASTILLO M, 1996, IMAGING PEDIAT HEAD, P155
  • [4] BRAIN GLUCOSE-UTILIZATION IN BAND HETEROTOPIA - SYNAPTIC ACTIVITY OF DOUBLE CORTEX
    DEVOLDER, AG
    GADISSEUX, JFA
    MICHEL, CJ
    MALOTEAUX, JMV
    BOL, AC
    GRANDIN, CB
    DUPREZ, TP
    EVRARD, P
    [J]. PEDIATRIC NEUROLOGY, 1994, 11 (04) : 290 - 294
  • [5] The constructive nature of vision: direct evidence from functional magnetic resonance imaging studies of apparent motion and motion imagery
    Goebel, R
    Khorram-Sefat, D
    Muckli, L
    Hacker, H
    Singer, W
    [J]. EUROPEAN JOURNAL OF NEUROSCIENCE, 1998, 10 (05) : 1563 - 1573
  • [6] MAGNETIC-RESONANCE-IMAGING AND POSITRON EMISSION TOMOGRAPHY OF BAND HETEROTOPIA
    MIURA, K
    WATANABE, K
    MAEDA, N
    MATSUMOTO, A
    KUMAGAI, T
    ITO, K
    KATO, T
    [J]. BRAIN & DEVELOPMENT, 1993, 15 (04) : 288 - 290
  • [7] Functional imaging in periventricular nodular heterotopia with the use of FDG-PET and HMPAO-SPECT
    Morioka, T
    Nishio, S
    Sasaki, M
    Yoshida, T
    Kuwabara, Y
    Ohta, M
    Fukui, M
    [J]. NEUROSURGICAL REVIEW, 1999, 22 (01) : 41 - 44
  • [8] Morioka T, 1999, NEUROSURG REV, V22, P99
  • [9] THE ASSESSMENT AND ANALYSIS OF HANDEDNESS: THE EDINBURGH INVENTORY
    OLDFIELD, RC
    [J]. NEUROPSYCHOLOGIA, 1971, 9 (01) : 97 - 113
  • [10] Cerebral activation in malformations of cortical development
    Richardson, MP
    Koepp, MJ
    Brooks, DJ
    Coull, JT
    Grasby, P
    Fish, DR
    Duncan, JS
    [J]. BRAIN, 1998, 121 : 1295 - 1304