Best design of heterogenized β-aminoalcohols for improvement of enantioselective addition of diethylzinc to benzaldehyde

被引：50

作者：

Abramson, S ^{[1
]}

Laspéras, M ^{[1
]}

Galarneau, A ^{[1
]}

Desplantier-Giscard, D ^{[1
]}

Brunel, D ^{[1
]}

机构：

[1] Ecole Natl Super Chim Montpellier, Lab Mat Catalyt & Catalyse Chim Organ, UMR 5618 CNRS, F-34296 Montpellier 5, France

来源：

CHEMICAL COMMUNICATIONS | 2000年 / 18期

关键词：

D O I：

10.1039/b005518m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Covalent immobilization of (1R,2S)-(-)-ephedrine, used as a model molecule of beta-aminoalcohols, on the surface of MCM-41-type mesoporous aluminosilicates, performed by a new sol-gel method, leads to chiral auxiliaries which show greatly enhanced rates and ee's compared to those reported up to now in the enantioselective addition of diethylzinc to benzaldehyde.

引用

页码：1773 / 1774

页数：2

共 15 条

[1]

ABRAMSON S, IN PRESS TOP CATAL

[2]

Bae SJ, 2000, CHEM COMMUN, P31

[3] Factors affecting the efficiency of hybrid chiral mesoporous silicas used as heterogeneous inorganic-organic catalysts in the enantioselective alkylation of benzaldehyde [J].