Coscinamides A, B and C, three new bis indole alkaloids from the marine sponge Coscinoderma sp.

被引：67
|
作者：
Bokesch, HR
Pannell, LK
McKee, TC
Boyd, MR [1 ]
机构：
[1] NCI, Lab Drug Discovery Res & Dev, Dev Therapeut Program, Div Canc Treatment & Diag,Fraderick Canc Res & De, Frederick, MD 21702 USA
[2] FCRDC, SAIC Frederick, Frederick, MD 21702 USA
[3] NIDDK, Bioorgan Chem Lab, NIH, Bethesda, MD 20892 USA
来源：
TETRAHEDRON LETTERS | 2000年 / 41卷 / 33期
基金：
美国国家卫生研究院;
关键词：
bis indole alkaloid; marine natural product; Coscinoderma;
D O I：
10.1016/S0040-4039(00)01062-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Three novel bis indole alkaloids, coscinamides A-C have been isolated from an extract of the marine sponge Coscinoderma sp., and their structures determined on the basis of spectral data, These compounds contain an unusual alpha-keto enamide functionality and are the first reported alkaloids from this genus, Published by Elsevier Science Ltd.
引用
收藏
页码：6305 / 6308
页数：4
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