When less is more - efficacy with less toxicity at the ED50

被引：29

作者：

Dimmitt, Simon ^{[2
,3
]}

Stampfer, Hans ^{[4
,5
]}

Martin, Jennifer H. ^{[1
,6
]}

机构：

[1] Univ Newcastle, Sch Med & Publ Hlth, Callaghan, NSW 2298, Australia

[2] Univ Western Australia, Sch Med & Pharmacol, 3-10 McCourt St, West Leederville 6007, Australia

[3] Australian Community & Hlth Fdn, West Leederville 6007, Australia

[4] Univ Western Australia, Joondalup Hlth Campus, Crawley, WA 6009, Australia

[5] Sir Charles Gairdner Hosp, Perth, WA, Australia

[6] Hunter New England Local Hlth Dist, Dept Med, Newcastle, NSW, Australia

来源：

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 2017年 / 83卷 / 07期

关键词：

dose-response; effective dose 50; pharmaceutical marketing; ACUTE CORONARY SYNDROMES; STATIN THERAPY; HEART-DISEASE; MORTALITY; METAANALYSIS; CHOLESTEROL; MORBIDITY;

D O I：

10.1111/bcp.13281

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：1365 / 1368

页数：4

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