The role of meniscal tissue in joint protection in early osteoarthritis

被引：81

作者：

Verdonk, Rene ^{[1
]}

Madry, Henning ^{[2
]}

Shabshin, Nogah ^{[3
,4
]}

Dirisamer, Florian ^{[5
]}

Peretti, Giuseppe M. ^{[6
,7
]}

Pujol, Nicolas ^{[8
]}

Spalding, Tim ^{[9
]}

Verdonk, Peter ^{[10
]}

Seil, Romain ^{[11
]}

Condello, Vincenzo ^{[12
]}

Di Matteo, Berardo ^{[13
,14
]}

Zellner, Johannes ^{[15
]}

Angele, Peter ^{[15
,16
]}

机构：

[1] Univ Ghent, De Pintelaan 185, B-9000 Ghent, Belgium

[2] Univ Saarland, Dept Orthopaed Surg, Med Ctr, Kirrberger Str 100,Bldg 37-38, D-66421 Homburg, Saarland, Germany

[3] Carmel Hosp, Dept Radiol, Haifa, Israel

[4] Hosp Univ Penn, Dept Radiol, 3400 Spruce St, Philadelphia, PA 19104 USA

[5] Schloss Puchenau, Orthopad & Sportchirurg, Karl Leitl Str 1, A-4048 Linz, Austria

[6] IRCCS Ist Ortoped Galeazzi, Milan, Italy

[7] Univ Milan, Dept Biomed Sci Hlth, Milan, Italy

[8] Ctr Hosp Versailles, 177 Rue Versailles, F-78150 Le Chesnay, France

[9] Univ Hosp Coventry & Warwickshire, Dept Orthopaed, Rugby, England

[10] Monica Hosp, Antwerp Orthoped Ctr, Antwerp, Belgium

[11] Ctr Hosp Luxembourg, Luxembourg Inst Hlth, Dept Orthopaed Surg, Clin Eich & Sports Med Res Lab, 78 Rue Eich, L-1460 Luxembourg, Luxembourg

[12] Osped Sacro Cuore Don Calabria, Strut Semplice Traumatol, Dipartimento Ortoped, Sport Knee Surg & Sports Traumatol, Via Don,Sempreboni 5, I-37024 Negrar Verona, Italy

[13] Ist Ortoped Rizzoli, Orthopaed Clin 2, Bologna, Italy

[14] Ist Ortoped Rizzoli, Biomech Lab, Bologna, Italy

[15] Univ Med Ctr Regensburg, Dept Trauma Surg, Franz Josef Strauss Allee 11, D-93042 Regensburg, Germany

[16] Sporthopaedicum Regensburg, Hildegard von Bingen Str 1, D-93053 Regensburg, Germany

来源：

KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY | 2016年 / 24卷 / 06期

关键词：

Meniscus; Early OA; Partial meniscectomy; Meniscal repair; Scaffold; Allograft; MESENCHYMAL STEM-CELLS; TERM-FOLLOW-UP; ARTHROSCOPIC PARTIAL MENISCECTOMY; PARTIAL MEDIAL MENISCECTOMY; DISCOID LATERAL MENISCUS; HIGH TIBIAL OSTEOTOMY; POLYURETHANE SCAFFOLD; KNEE OSTEOARTHRITIS; CARTILAGE LOSS; HIGH-SIGNAL;

D O I：

10.1007/s00167-016-4069-2

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

It is widely accepted that partial meniscectomy leads to early onset of osteoarthritis (OA). A strong correlation exists between the amount and location of the resected meniscus and the development of degenerative changes in the knee. On the other hand, osteoarthritic changes of the joint alter the structural and functional integrity of meniscal tissue. These alterations might additionally compromise the limited healing capacity of the meniscus. In young, active patients without cartilage damage, meniscus therapy including partial meniscectomy, meniscus suture, and meniscus replacement has proven beneficial effects in long-term studies. Even in an early osteoarthritic milieu, there is a relevant regenerative potential of the meniscus and the surrounding cartilage. This potential should be taken into account, and meniscal surgery can be performed with the correct timing and the proper indication even in the presence of early OA. Level of evidence IV.

引用

页码：1763 / 1774

页数：12

共 95 条

[1]

ABDON P, 1990, CLIN ORTHOP RELAT R, P166

[2] Deleterious effects of osteoarthritis on the structure and function of the meniscal enthesis [J].