Studies on synthesis of water-soluble polymer-supported transition metal polypyridyl complexes and their interaction with DNA

被引：1

作者：

Wang, YP ^{[1
]}

Zhang, FA ^{[1
]}

Zhang, HT ^{[1
]}

Li, YF ^{[1
]}

机构：

[1] NW Normal Univ, Inst Polymer, Lanzhou 730070, Peoples R China

来源：

JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS | 2004年 / 19卷 / 06期

关键词：

transition metal polypyridyl complexes; polymer synthesis; DNA; interaction;

D O I：

10.1177/0883911504048326

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Five water-soluble polymer-supported transition metal polypyridyl complexes were synthesized from poly(acrylic acid-co-N-vinyl pyrrolidone) with 2-methyl-3-hydroxyl benzaldehyde, o-phenanthroline and metal acetate salts. Infrared spectra (IR), thermo-gravimetric and differential thermal analysis (TG-DTA), Inductance Coupling Plasma (ICP) and X-ray photoelectron spectroscopy (XPS) were used to characterize these composites and structures. The interaction with DNA was studied by the fluorescent probe and gel electrophoresis methods. The results indicated that these complexes had strong interactions with DNA.

引用

页码：481 / 490

页数：10

共 14 条

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