Endogenous DNA breaks: γH2AX and the role of telomeres

被引：20

作者：

Olive, Peggy L. ^{[1
]}

机构：

[1] British Columbia Canc Res Ctr, Dept Med Biophys, Vancouver, BC V5Z 1L3, Canada

来源：

AGING-US | 2009年 / 1卷 / 02期

关键词：

DNA damage; cancer; cell cycle; histone; DNA repair; DOUBLE-STRAND BREAKS; PHOSPHORYLATED HISTONE H2AX; IN-VIVO; CELLS; INSTABILITY; LESIONS; REPAIR; FOCI;

D O I：

10.18632/aging.100025

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

[No abstract available]

引用

页码：154 / 156

页数：3

共 17 条

[1]

BANATH JP, 2009, EXP CELL RE IN PRESS

[2] OPINION γH2AX and cancer [J].

Bonner, William M. ;

Redon, Christophe E. ;

Dickey, Jennifer S. ;

Nakamura, Asako J. ;

Sedelnikova, Olga A. ;

Solier, Stephanie ;

Pommier, Yves .

NATURE REVIEWS CANCER, 2008, 8 (12) :957-967

[3] Protection of mammalian telomeres [J].

de Lange, T .

ONCOGENE, 2002, 21 (04) :532-540

[4] DNA DOUBLE-STRAND BREAKS - THEIR REPAIR AND RELATIONSHIP TO CELL KILLING IN YEAST [J].

FRANKENBERGSCHWAGER, M ;

FRANKENBERG, D .

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 1990, 58 (04) :569-575

[5] Telomere aggregates in non-Hodgkin lymphoma patients at different disease stages [J].

Goldberg-Bittman, L. ;

Kitay-Cohen, Y. ;

Quitt, M. ;

Hadary, R. ;

Fejgin, M. D. ;

Yukla, M. ;

Amiel, A. .

CANCER GENETICS AND CYTOGENETICS, 2008, 184 (02) :105-108

[6] In vivo formation and repair of DNA double-strand breaks after computed tomography examinations [J].

Löbrich, M ;

Rief, N ;

Kühne, M ;

Heckmann, M ;

Fleckenstein, J ;

Rübe, C ;

Uder, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (25) :8984-8989

[7] The significance of telomeric aggregates in the interphase nuclei of tumor cells [J].

Mai, S ;

Garini, Y .

JOURNAL OF CELLULAR BIOCHEMISTRY, 2006, 97 (05) :904-915

[8] ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells [J].

McManus, KJ ;

Hendzel, MJ .

MOLECULAR BIOLOGY OF THE CELL, 2005, 16 (10) :5013-5025

[9] Telomeres and chromosome instability [J].

Murnane, John P. .

DNA REPAIR, 2006, 5 (9-10) :1082-1092

[10] Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence [J].

Nakamura, Asako J. ;

Chiang, Y. Jeffrey ;

Hathcock, Karen S. ;

Horikawa, Izumi ;

Sedelnikova, Olga A. ;

Hodes, Richard J. ;

Bonner, William M. .

EPIGENETICS & CHROMATIN, 2008, 1 (1)

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