Experience with the wearable cardioverter-defibrillator in older patients: Results from the Prospective Registry of Patients Using the Wearable Cardioverter-Defibrillator

被引:12
作者
Daimee, Usama A. [1 ]
Vermilye, Katherine [1 ]
Moss, Arthur J. [1 ]
Goldenberg, Ilan [1 ]
Klein, Helmut U. [1 ]
McNitt, Scott [1 ]
Zareba, Wojciech [1 ]
Kutyifa, Valentina [1 ]
机构
[1] Univ Rochester, Med Ctr, Div Cardiol, Heart Res Follow Up Program, 265 Crittenden Blvd,Box 653, Rochester, NY 14642 USA
关键词
Compliance; Implantable cardioverter-defibrillator; Older patients; Ventricular tachyarrhythmias; Wearable cardioverter-defibrillator; ACUTELY TERMINATING EPISODES; HIGH-RISK; VENTRICULAR-FIBRILLATION; ATRIAL-FIBRILLATION; CLINICAL-EFFICACY; DYSFUNCTION; INFARCTION; THERAPY; SHOCKS;
D O I
10.1016/j.hrthm.2018.04.014
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND Use of the wearable cardioverter-defibrillator (WCD) in older patients has not been described previously. OBJECTIVE The purpose of this study was to assess WCD wear time, risk of arrhythmic events during WCD use, and implantable cardioverter-defibrillator (ICD) implantation rates after the end of WCD use in patients with age >= 65 years vs <65 years. METHODS We stratified 1732 patients with ischemic and nonischemic cardiomyopathy from the Prospective Registry of Patients Using the Wearable Defibrillator Registry into 2 subgroups by age: those with age >= 65 years and those with age <65 years. Wear time, arrhythmic events, and end-of-use decisions, specifically ICD implantation or improvement in ejection fraction, were evaluated for each age group. RESULTS There were 722 patients with age >= 65 years (41.7%) and 1010 patients with age <65 years (58.3%). Daily WCD wear time was longer in the older population (median 22.8 h/d (IQR 21.5 23.2) vs 22.3 h/d (IQR 19.5- 23.0); P <.001). Patients with age >= 65 years experienced higher event rates, per 100 patient-years, for any sustained ventricular tachycardia/ventricular fibrillation (31.95 vs 9.82; P =.027) and ventricular tachycardia/ventricular fibrillation treated with WCD shock (6.92 vs 2.37; P =.034), particularly with ischemic cardiomyopathy. Younger patients experienced a trend toward a higher event rate for atrial arrhythmias with nonischemic cardiomyopathy (150.07 vs 74.86; P =.055). At the end of WCD use, ICD implantation was more frequent in older patients (41.8% vs 36.5%; P =.034). CONCLUSION Older patients had good compliance with the WCD, presented with more frequent ventricular arrhythmias, and were more likely to receive an ICD at the end of WCD use. The WCD may play a role in risk stratification of the older population.
引用
收藏
页码:1379 / 1386
页数:8
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