Uncommon presentation of venous thromboembolism and fatal systemic emboli in a patient with nonbacterial thrombotic endocarditis due to pancreatic cancer

被引：0

作者：

Elikowski, Waldemar ^{[1
]}

Lazowski, Stanislaw ^{[2
]}

Malek, Malgorzata ^{[1
]}

Wroblewski, Dariusz ^{[1
]}

Kuzniacka-Kaczor, Ewa ^{[1
]}

Skowronski, Marcin ^{[3
]}

机构：

[1] Szpital Im J Strusia, Oddziat Chorob Wewnetrznych, PL-61833 Poznan, Poland

[2] Szpital Im J Strusia, Pracownia Anat Patologicznej, PL-61833 Poznan, Poland

[3] Szpital Im J Strusia, Szpitalny Oddziat Ratunkowy, Poznan, Poland

来源：

KARDIOLOGIA POLSKA | 2010年 / 68卷 / 06期

关键词：

tricuspid valve thrombus; nonbacterial thrombotic endocarditis; pancreatic cancer; DISSEMINATED INTRAVASCULAR COAGULATION; TRICUSPID-VALVE THROMBUS; PATHOGENESIS; DIAGNOSIS; RISK;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In the presented case of a 60-year-old man, deep vein thrombosis and pulmonary embolism symptoms preceded pancreatic cancer diagnosis. An unexpected echocardiographic finding was a longitudinal mass attached to the tricuspid valve, and extending to the pulmonary artery - suggestive of a thrombus (as confirmed further autopsy), probably embolic in origin. This uncommon situation might be due to nonbacterial thrombotic endocarditis, which involved all, but mainly tricuspid and aortic valves. During heparin therapy the patient's haemodynamic status was stable until systemic emboli occurred with multifocal ischaemic stroke that was the cause of death.

引用

页码：678 / 683

页数：6

共 26 条

[11]

JAMESON GS, 2009, GASTROENTEROLOGY, V3, P67

[12] Pancreatic cancer and thromboembolic disease [J].

Khorana, AA ;

Fine, RL .

LANCET ONCOLOGY, 2004, 5 (11) :655-663

[13]

KIM HS, 1977, ARCH PATHOL LAB MED, V101, P65

[14] Nonbacterial thrombotic endocarditis involving all four cardiac valves [J].

Laco, Jan ;

Steiner, Ivo ;

Havel, Eduard .

PATHOLOGY RESEARCH AND PRACTICE, 2008, 204 (10) :757-761

[15]

Llenas-García J, 2007, REV ESP CARDIOL, V60, P493, DOI 10.1016/S1885-5857(07)60190-X

[16] Venous thromboembolism predicts poor prognosis in irresectable pancreatic cancer patients [J].

Mandala, M. ;

Reni, M. ;

Cascinu, S. ;

Barni, S. ;

Floriani, I. ;

Cereda, S. ;

Berardi, R. ;

Mosconi, S. ;

Torri, V. ;

Labianca, R. .

ANNALS OF ONCOLOGY, 2007, 18 (10) :1660-1665

[17] Venous thromboembolism and pancreatic cancer:: Incidence, pathogenesis and clinical implications [J].

Mandala, Mario ;

Moro, Cecilia ;

Labianca, Roberto .

ONKOLOGIE, 2008, 31 (03) :129-135

[18] Risk of venous thrombosis in patients with pancreatic adenocarcinoma [J].

Mitry, Emmanuel ;

Taleb-Fayad, Raffic ;

Deschamps, Antoine ;

Mansencal, Nicolas ;

Lepere, Celine ;

Declety, Gilles ;

Lievre, Astrid ;

Vaillant, Jean-Nicolas ;

Lesur, Gilles ;

Cramer, Elisabeth ;

Dubourg, Olivier ;

Rougier, Philippe .

GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE, 2007, 31 (12) :1139-1142

[19] Inferior vena caval tumor thrombus extending into the right atrium in a patient with pancreatic cancer [J].

Ozben, Beste ;

Papila, Nurdan ;

Tanrikulu, M. Azra ;

Bayalan, Fatih ;

Fak, Ali Serdar ;

Oktay, Ahmet .

JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 2007, 24 (03) :317-321

[20]

OZKUTLU S, 1991, JPN HEART J, V32, P139

← 1 2 3 →