Seasonal variations in the onset and healing rates of venous leg ulcers

被引:6
作者
Simka, M. [1 ]
机构
[1] Private Healthcare Inst SANA, Dept Angiol, Pszczyna, Poland
关键词
leg ulcer; seasonal variations; venous insufficiency; wound healing; LYMPHOCYTE SUBSETS; INTERFERON-GAMMA; BLOOD; DISEASE; MECHANISMS; RATIO;
D O I
10.1258/phleb.2009.008072
中图分类号
R61 [外科手术学];
学科分类号
摘要
Objectives: As many vascular pathologies exhibit circannual fluctuation, the aim of this study was to assess the chronobiological features of venous ulcers. Methods: Based on a retrospective survey of the case histories of 391 venous ulcer patients, the rates of ulcer onset and healing in each month were analysed statistically; a time series was constructed to evaluate the seasonality. Results: There was a significantly higher frequency of ulcer onset during the warmer part of the year (April-October), and onset showed strong seasonality. Healing rates were also unequally and statistically significantly distributed throughout the year: ulcers that appeared or that were treated with specialized treatment in the winter or summer healed slower in comparison to ulcers that began in the spring or autumn. Conclusions: Venous ulcers exhibit circannual fluctuations in their onset and healing rates. Hypothetically, in addition to exacerbation of chronic venous insufficiency, seasonal variations in immune system activity might potentially be responsible for this phenomenon.
引用
收藏
页码:29 / 34
页数:6
相关论文
共 50 条
[41]   Exercise for Leg Ulcers "Working Out" the Nature of Venous Ulcers [J].
Kirsner, Robert S. .
JAMA DERMATOLOGY, 2018, 154 (11) :1257-1259
[42]   Association of biofilm and microbial metrics with healing rate in older adults with chronic venous leg ulcers [J].
Stewart, Philip S. ;
Kim, Junglyun ;
James, Garth ;
Yi, Fan ;
Stechmiller, Joyce ;
Weaver, Michael ;
Kelly, Debra L. ;
Fisher, Steve ;
Schultz, Gregory ;
Lyon, Debra .
WOUND REPAIR AND REGENERATION, 2024, 32 (06) :858-871
[43]   Meta-analytic approaches to determine gender differences for delayed healing in venous leg ulcers [J].
Tang, Xiao-Lei ;
Chen, Hong-Lin ;
Zhao, Fang-Fang .
PHLEBOLOGY, 2016, 31 (10) :744-752
[44]   High voltage stimulation for healing acceleration of venous leg ulcers - Usefulness after surgical treatment [J].
Franek, A ;
Taradaj, J ;
Cierpka, L ;
Blaszczak, E .
PHLEBOLOGIE, 2005, 34 (05) :255-260
[45]   Calf muscle pump impairment and delayed healing of venous leg ulcers: Air plethysmographic findings [J].
Simka, Marian .
JOURNAL OF DERMATOLOGY, 2007, 34 (08) :537-544
[46]   The association of wound factors and symptoms of fatigue and pain with wound healing in chronic venous leg ulcers [J].
Kim, Junglyun ;
Stechmiller, Joyce ;
Weaver, Michael ;
Gibson, Daniel J. ;
Horgas, Ann ;
Kelly, Debra L. ;
Lyon, Debra E. .
INTERNATIONAL WOUND JOURNAL, 2023, 20 (04) :1098-1111
[47]   The Effect of Bacterial Colonization and Maggot Debridement Treatment on Wound Healing in Chronic Venous Leg Ulcers [J].
Sirekbasan, Serhat ;
Polat, Erdal ;
Cangel, Ugur .
CLINICAL LABORATORY, 2021, 67 (05) :1289-1292
[48]   Doxycycline speeds up healing of chronic venous ulcers [J].
Serra, Raffaele ;
Gallelli, Luca ;
Buffone, Gianluca ;
Molinari, Vincenzo ;
Stillitano, Domenico M. ;
Palmieri, Camillo ;
de Franciscis, Stefano .
INTERNATIONAL WOUND JOURNAL, 2015, 12 (02) :179-184
[49]   Tissue oxygenation, perfusion, and position in patients with venous leg ulcers [J].
Wipke-Tevis, DD ;
Stotts, NA ;
Williams, DA ;
Froelicher, ES ;
Hunt, TK .
NURSING RESEARCH, 2001, 50 (01) :24-32
[50]   Modified compression therapy in mixed arterial-venous leg ulcers: An integrative review [J].
Lim, Sheryl Li Xin ;
Chung, Rui En ;
Holloway, Samantha ;
Harding, Keith G. .
INTERNATIONAL WOUND JOURNAL, 2021, 18 (06) :822-842