Base-Controlled One-Pot Chemoselective Suzuki-Miyaura Reactions for the Synthesis of Unsymmetrical Terphenyls

被引：3

作者：

Li, Xinmin ^{[1
]}

Feng, Fangfang ^{[1
]}

Ren, Changyue ^{[1
]}

Teng, Yong ^{[1
]}

Hu, Qinghong ^{[1
]}

Yuan, Zeli ^{[1
]}

机构：

[1] Zunyi Med Univ, Sch Pharm, Zunyi 563000, Guizhou, Peoples R China

来源：

SYNLETT | 2019年 / 30卷 / 19期

关键词：

chemoselective; Suzuki-Miyaura reactions; unsymmetrical terphenyls; one-pot; ligand-free; CROSS-COUPLING REACTIONS; DERIVATIVES; PYRIDINES; SUFEX;

D O I：

10.1055/s-0039-1690227

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report a chemoselective Suzuki-Miyaura reaction protocol of using bromophenyl fluorosulfonate as building block for the preparation of unsymmetrical terphenyls. The chemoselective cross-coupling of bromophenyl fluorosulfonate and arylboronic acids can be achieved by controlling base species without using any ligands. Under this methodology, various of m- and p-unsymmetrical terphenyls were obtained in moderate to good yields.

引用

页码：2131 / 2135

页数：5

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