Multiple Pilus Motors Cooperate for Persistent Bacterial Movement in Two Dimensions

被引：49

作者：

Holz, Claudia ^{[1
]}

Opitz, Dirk ^{[1
]}

Greune, Lilo ^{[2
]}

Kurre, Rainer ^{[1
]}

Koomey, Michael ^{[3
,4
]}

Schmidt, M. Alexander ^{[2
]}

Maier, Berenike ^{[1
]}

机构：

[1] Univ Munster, Inst Mol Zellbiol, D-4400 Munster, Germany

[2] Univ Munster, Inst Infektiol, Zentrum Mol Biol Entzundung, D-4400 Munster, Germany

[3] Univ Oslo, Ctr Mol Biol & Neurosci, N-0316 Oslo, Norway

[4] Univ Oslo, Dept Mol Biosci, N-0316 Oslo, Norway

来源：

PHYSICAL REVIEW LETTERS | 2010年 / 104卷 / 17期

关键词：

NEISSERIA-GONORRHOEAE; IV PILI; RETRACTION; MOTILITY; DYNAMICS;

D O I：

10.1103/PhysRevLett.104.178104

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

In various bacterial species surface motility is mediated by cycles of type IV pilus motor elongation, adhesion, and retraction, but it is unclear whether bacterial movement follows a random walk. Here we show that the correlation time of persistent movement in Neisseria gonorrhoeae increases with the number of pili. The unbinding force of individual pili from the surface F = 10 pN was considerably lower than the stalling force F > 100 pN, suggesting that density, force, and adhesive properties of the pilus motor enable a tug-of-war mechanism for bacterial movement.

引用

页数：4

共 16 条

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