Qualitative analysis of a mathematical model for capillary formation in tumor angiogenesis

被引:18
作者
Pamuk, S [1 ]
机构
[1] Univ Kocaeli, Dept Math, TR-41300 Ataturk Bulvari, Izmit, Turkey
基金
美国国家科学基金会;
关键词
capillary; angiogenesis; quasi-steady state; probability density function; stability;
D O I
10.1142/S0218202503002362
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
Qualitative analysis of a mathematical model for capillary formation is presented under assumptions that enzyme and fibronectin concentrations are in quasi-steady state. The aim of this paper is to prove mathematically that the long-time tendency of endothelial cells will be towards the transition probability density function of enzyme and fibronectin. Endothelial cell steady-state solution is obtained and a numerical simulation is provided to show that there is a close agreement between the steady-state solution obtained analytically and the numerically calculated steady-state of the related initial value problem, which provides strong evidence for the stability of this steady-state.
引用
收藏
页码:19 / 33
页数:15
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