Going in Circles: The Black Box of Circular RNA Immunogenicity

被引：9

作者：

Basavappa, Megha G. ^{[1
]}

Cherry, Sara ^{[1
]}

机构：

[1] Univ Penn, Dept Microbiol, Philadelphia, PA 19104 USA

来源：

MOLECULAR CELL | 2019年 / 76卷 / 01期

关键词：

RECOGNITION; ACTIVATION;

D O I：

10.1016/j.molcel.2019.08.027

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two recent papers in Molecular Cell (Chen et al., 2019; Wesselhoeft et al., 2019) have probed the putative immunogenicity of circular RNAs (circRNAs). These studies indicate that the stimulatory capacity of circRNAs depends on factors including the specific RNA, the mode of biogenesis, RNA modifications, cell type, and the means of delivery.

引用

页码：3 / 5

页数：4

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