The synthesis of cycloalka[b]furans via an Au(I)-catalyzed tandem reaction of 3-yne-1,2-diols

被引：5

作者：

Liu, Wei-Ting ^{[1
]}

Xu, Zheng-Liang ^{[1
]}

Mou, Xue-Qing ^{[1
]}

Zhang, Bang-Hong ^{[1
]}

Bao, Wen ^{[1
]}

Wang, Shao-Hua ^{[1
,2
,3
]}

Lee, Dongjun ^{[1
]}

Lei, Lin-Sheng ^{[1
]}

Zhang, Kun ^{[2
]}

机构：

[1] Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China

[2] Wuyi Univ, Sch Chem & Environm Engn, Jiangmen 529020, Peoples R China

[3] Sichuan Univ, Minist Educ, Key Lab Drug Targeting & Drug Delivery Syst, Chengdu, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2017年 / 15卷 / 30期

关键词：

HIGHLY SUBSTITUTED FURANS; BAND-GAP POLYMERS; ELECTROPHILIC CYCLIZATION; MULTISUBSTITUTED FURANS; EFFICIENT SYNTHESIS; CARBOXYLIC-ACIDS; NATURAL-PRODUCTS; GOLD CATALYSIS; MODULAR ENTRY; 2-(1-ALKYNYL)-2-ALKEN-1-ONES;

D O I：

10.1039/c7ob01179b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An Au(I)-catalyzed cyclization/1,2-rearrangement/aromatization cascade of 3-yne-1,2-diols has been successfully realized. This reaction not only provides a new and efficient strategy for the synthesis of substituted cycloalka[b]furan compounds as well as their derivatives, but might also facilitate related biological studies.

引用

页码：6333 / 6337

页数：5

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