Ruthenium-catalyzed synthesis of N-substituted lactams by acceptorless dehydrogenative coupling of diols with primary amines

被引：25

作者：

Zheng, Yanling ^{[1
]}

Nie, Xufeng ^{[1
]}

Long, Yang ^{[1
]}

Ji, Li ^{[1
]}

Fu, Haiyan ^{[1
]}

Zheng, Xueli ^{[1
]}

Chen, Hua ^{[1
]}

Li, Ruixiang ^{[1
]}

机构：

[1] Sichuan Univ, Coll Chem, Minist Educ, Key Lab Green Chem & Technol, 29 Wangjiang Rd, Chengdu 610064, Sichuan, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 82期

基金：

中国国家自然科学基金;

关键词：

AMIDE SYNTHESIS; TRICYCLIC ANALOGS; CYCLIC IMIDES; ALCOHOLS; ALKYLATION; OXIDATION; HYDROGEN; LIBERATION; ANILINES; ACCESS;

D O I：

10.1039/c9cc06339k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein, we report the first example of synthesis of N-substituted lactams via an acceptorless dehydrogenative coupling of diols with primary amines in one step, which was enabled by combining Ru-3(CO)(12) with a hybrid N-heterocyclic carbene-phosphine-phosphine ligand as the catalyst.

引用

页码：12384 / 12387

页数：4

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