A Quinoline-thiooxorhodamine Conjugate for Fluorescent Hg2+ Recognition in Aqueous Media and Living Cells

被引：0
作者：
Tang, Lijun [1 ]
Wen, Xin [1 ]
Dai, Xin [1 ]
Wu, Di [1 ]
Huang, Zhenlong [1 ]
机构：
[1] Bohai Univ, Dept Chem, Liaoning Prov Key Lab Synth & Applicat Funct Cpds, Jinzhou 121013, Peoples R China
来源：
BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2014年 / 35卷 / 11期
关键词：
Fluorescence; Hg(II) recognition; Rhodamine; Cell imaging; SELECTIVE FLUORESCENT; RHODAMINE; CHEMOSENSORS; MERCURY; SENSOR;
D O I：
10.5012/bkcs.2014.35.11.3326
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A quinoline-thiooxorhodamine conjugate fluorescent sensor (1) has been synthesized. Sensor 1 exhibits high selectivity and sensitivity to Hg2+ in H2O/DMSO (95/5, v/v, HEPES 20 mM, pH = 7.4) solution with fluorescence detection. Other tested metal ions do not induce any significant fluorescence intensity changes. Sensor 1 interacts with Hg2+ through a 1:1 binding stoichiometry with a good anti-inference ability. In addition, fluorescent imaging of Hg2+ in Hela cells is also successfully demonstrated.
引用
收藏
页码：3326 / 3330
页数：5
相关论文
共 28 条
  • [1] Synthesis and applications of Rhodamine derivatives as fluorescent probes
    Beija, Mariana
    Afonso, Carlos A. M.
    Martinho, Jose M. G.
    [J]. CHEMICAL SOCIETY REVIEWS, 2009, 38 (08) : 2410 - 2433
  • [2] Rhombus-Shaped Tetranuclear [Ln4] Complexes [Ln = Dy(III) and Ho(III)]: Synthesis, Structure, and SMM Behavior
    Chandrasekhar, Vadapalli
    Hossain, Sakiat
    Das, Sourav
    Biswas, Sourav
    Sutter, Jean-Pascal
    [J]. INORGANIC CHEMISTRY, 2013, 52 (11) : 6346 - 6353
  • [3] Fluorescent Chemosensors Based on Spiroring-Opening of Xanthenes and Related Derivatives
    Chen, Xiaoqiang
    Pradhan, Tuhin
    Wang, Fang
    Kim, Jong Seung
    Yoon, Juyoung
    [J]. CHEMICAL REVIEWS, 2012, 112 (03) : 1910 - 1956
  • [4] CONNER KA, 1987, BINDING CONSTANTS ME
  • [5] Rhodamine and BODIPY chemodosimeters and chemosensors for the detection of Hg2+, based on fluorescence enhancement effects
    Culzoni, M. J.
    Munoz de la Pena, A.
    Machuca, A.
    Goicoechea, H. C.
    Babiano, R.
    [J]. ANALYTICAL METHODS, 2013, 5 (01) : 30 - 49
  • [6] Signaling recognition events with fluorescent sensors and switches
    de Silva, AP
    Gunaratne, HQN
    Gunnlaugsson, T
    Huxley, AJM
    McCoy, CP
    Rademacher, JT
    Rice, TE
    [J]. CHEMICAL REVIEWS, 1997, 97 (05) : 1515 - 1566
  • [7] Fluorescent chemodosimeters using "mild" chemical events for the detection of small anions and cations in biological and environmental media
    Du, Jianjun
    Hu, Mingming
    Fan, Jiangli
    Peng, Xiaojun
    [J]. CHEMICAL SOCIETY REVIEWS, 2012, 41 (12) : 4511 - 4535
  • [8] New fluorescent chemosensors for metal ions in solution
    Formica, Mauro
    Fusi, Vieri
    Giorgi, Luca
    Micheloni, Mauro
    [J]. COORDINATION CHEMISTRY REVIEWS, 2012, 256 (1-2) : 170 - 192
  • [9] Bifunctional Fluoroionphore-Ionic Liquid Hybrid for Toxic Heavy Metal Ions: Improving Its Performance via the Synergistic Extraction Strategy
    Jin, Zhen
    Xie, De-Xun
    Zhang, Xiao-Bing
    Gong, Yi-Jun
    Tan, Weihong
    [J]. ANALYTICAL CHEMISTRY, 2012, 84 (10) : 4253 - 4257
  • [10] "Turn-on" fluorescent sensing with "reactive" probes
    Jun, Mi Eun
    Roy, Basab
    Ahn, Kyo Han
    [J]. CHEMICAL COMMUNICATIONS, 2011, 47 (27) : 7583 - 7601
123