Concept of T-Wave Morphology Dispersion

The detection of ventricular repolarisation abnormalities is widely being done using the Qr interval measurements. However; there ore both technical and theoretical problems with QT measurements. We propose two robust methods for the quantification of the ventricular repolarisation abnormalities: i) The quantification of the inter-lead morphology differences of the T wave (T Wave Morphology Dispersion - TMD) ii) The analysis of the T wave wavefront direction with respect to the QRS complex (Total Cosine R_To_T - TCRT). Sensitivity nod specificity of 82% (84%) in supine position and 77% (79%) in standing position were achieved for TMD (TCRT). Both parameters were more reproducible than conventional QT interval based parameters.