Ultrasound assisted one-pot synthesis of benzo-fused indole-4,9-dinones from 1,4-naphthoquinone and α-aminoacetals

被引：11

作者：

Luu, Quang H. ^{[1
]}

Guerra, Jorge D. ^{[1
]}

Castaneda, Cecilio M. ^{[1
]}

Martinez, Manuel A. ^{[1
]}

Saunders, Jong ^{[1
]}

Garcia, Benjamin A. ^{[2
]}

Gonzales, Brenda V. ^{[2
]}

Aidunuthula, Anushritha R. ^{[2
]}

Mito, Shizue ^{[1
,2
]}

机构：

[1] Univ Texas El Paso, Dept Chem, El Paso, TX 79968 USA

[2] Univ Texas Rio Grande Valley, Dept Chem, Edinburg, TX 78539 USA

来源：

TETRAHEDRON LETTERS | 2016年 / 57卷 / 21期

关键词：

p-Indolequinone; Cyclization; One-pot reaction; Ultrasound-assisted; Heterocycles; PALLADIUM-PROMOTED SYNTHESIS; CATALYZED TOTAL-SYNTHESIS; MURRAYAQUINONE-A; DERIVATIVES; ALKALOIDS; INDOLEQUINONES; ENAMINES; INDOLOQUINONES; BROMOQUINONES; FUROSTIFOLINE;

D O I：

10.1016/j.tetlet.2016.04.031

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot synthesis of benzo[f]indole-4,9-diones from 1,4-naphthoquinone with alpha-aminoacetals has been developed. This method provides a straightforward synthesis of benzo[f]indole-4,9-diones via intramolecular nucleophilic attack of aminoquinones to aldehydes under mild reaction conditions. The detailed mechanism was also investigated. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：2253 / 2256

页数：4

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