Impact of Bundle Branch Block on Permanent Pacemaker Implantation after Transcatheter Aortic Valve Implantation: A Meta-Analysis

被引：11

作者：

Ravaux, Justine M. ^{[1
]}

Di Mauro, Michele ^{[1
]}

Vernooy, Kevin ^{[2
,3
,4
]}

Mariani, Silvia ^{[1
]}

Ronco, Daniele ^{[1
,5
]}

Simons, Jorik ^{[1
]}

Van't Hof, Arnoud W. ^{[2
,3
]}

Veenstra, Leo ^{[2
]}

Kats, Suzanne ^{[1
]}

Maessen, Jos G. ^{[1
,3
]}

Lorusso, Roberto ^{[1
,3
]}

机构：

[1] Maastricht Univ Med Ctr MUMC, Heart & Vasc Ctr, Dept Cardiothorac Surg, NL-6202 AZ Maastricht, Netherlands

[2] Maastricht Univ Med Ctr MUMC, Dept Cardiol, NL-6202 AZ Maastricht, Netherlands

[3] Maastricht Univ Med Ctr, Cardiovasc Res Inst Maastricht CARIM, NL-6202 AZ Maastricht, Netherlands

[4] Radboud Univ Med Ctr Radboudumc, Dept Cardiol, NL-6525 GA Nijmegen, Netherlands

[5] Univ Insubria, Circolo Hosp, Dept Med & Surg, I-21100 Varese, VA, Italy

来源：

JOURNAL OF CLINICAL MEDICINE | 2021年 / 10卷 / 12期

关键词：

transcatheter aortic valve implantation; right bundle branch block; left bundle branch block; permanent pacemaker implantation; CLINICAL-OUTCOMES; ATRIOVENTRICULAR-BLOCK; HEART-BLOCK; PREDICTORS; REPLACEMENT; RISK; COREVALVE; HETEROGENEITY; CONDUCTION; TAVI;

D O I：

10.3390/jcm10122719

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Data regarding the impact of infra-Hisian conduction disturbances leading to permanent pacemaker implantation (PPI) after transcatheter aortic valve implantation (TAVI) remain limited. The aim of this study was to determine the impact of right and/or left bundle branch block (RBBB/LBBB) on post-TAVI PPI. We performed a systematic literature review to identify studies reporting on RBBB and/or LBBB status and post-TAVI PPI. Study design, patient characteristics, and the presence of branch block were analyzed. Odds ratios (ORs) with 95% CI were extracted. The final analysis included 36 studies, reporting about 55,851 patients. Data on LBBB were extracted from 33 studies. Among 51,026 patients included, 5503 showed pre-implant LBBB (11.9% (10.4%-13.8%)). The influence of LBBB on post-TAVI PPI was not significant OR 1.1474 (0.9025; 1.4588), p = 0.2618. Data on RBBB were extracted from 28 studies. Among 46,663 patients included, 31,603 showed pre-implant RBBB (9.2% (7.3%-11.6%)). The influence of RBBB on post-TAVI PPI was significant OR 4.8581 (4.1571; 5.6775), p < 0.0001. From this meta-analysis, the presence of RBBB increased the risk for post-TAVI PPI, independent of age or LVEF, while this finding was not confirmed for patients experimenting with LBBB. This result emphasizes the need for pre-operative evaluation strategies in patient selection for TAVI.

引用

页数：20