Central corneal delle as a complication of erythema multiforme major

Purpose: To report a case of erythema multiforme major complicated by a central corneal delle. Methods: Case report. Results: An 18-year-old man recovering from erythema multiforme major complained of blurred vision and grittiness. Slit-lamp examination revealed a central corneal depression; the overlying epithelium was intact, and the stroma was thinned but lacked inflammation. The patient underwent 2 months of treatment with lubrication and autologous serum. The thinning corneal stroma thickened, and the corneal curvature returned to normal without any further complications such as corneal perforation. Conclusions: Erythema multiforme major caused upper tarsus deformity and dry eye, which resulted in localized corneal dehydration and a central corneal delle.