Metallocene sulfoxides as precursors of metallocenes with planar chirality

被引：75

作者：

Ferber, Benoit ^{[1
]}

Kagan, Henri B. ^{[1
]}

机构：

[1] Univ Paris 11, ICMMO, CNRS, UMR 8182, F-914055 Orsay, France

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2007年 / 349卷 / 4-5期

关键词：

chiral ligands; enantioselective catalysis; ferrocenes; lithiation; planar chirality; sulfoxides;

D O I：

10.1002/adsc.200600639

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The preparation of metallocene sulfoxides and their ortho-diastereoselective functionalization are described. The applications of enantiopure 1,2- and 1,3-disubstituted metallocenes are reviewed, with special emphasis on the preparation of ligands for asymmetric catalysis. The sulfoxide functionality is a useful, traceless, chiral diastereoselective ortho-directing group, as explained in the article. It allows one to synthesize a wide range of enantiopure metallocenes with planar chirality and predictible configuration. Most of the examples are related to the ferrocene area.

引用

页码：493 / 507

页数：15

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