Neural classification of Norwegian radiology reports: using NLP to detect findings in CT-scans of children

被引:11
作者
Dahl, Fredrik A. [1 ,2 ]
Rama, Taraka [3 ]
Hurlen, Petter [4 ]
Brekke, Pal H. [5 ]
Husby, Haldor [2 ]
Gundersen, Tore [6 ]
Nytro, Oystein [7 ]
Ovrelid, Lilja [8 ]
机构
[1] Akershus Univ Hosp, Hlth Serv Res Unit, Lorenskog, Norway
[2] Univ Oslo, Inst Clin Med, Campus Ahus, Oslo, Norway
[3] Univ North Texas, Dept Linguist, Denton, TX 76203 USA
[4] Akershus Univ Hosp, Div Diagnost & Technol, Lorenskog, Norway
[5] Natl Hosp Norway, Oslo Univ Hosp, Dept Cardiol, Oslo, Norway
[6] Akershus Univ Hosp, Data & Analyt, Lorenskog, Norway
[7] Norwegian Univ Sci & Technol, Dept Comp Sci, Trondheim, Norway
[8] Univ Oslo, Dept Informat, Oslo, Norway
关键词
Tomography; X-ray computed; Machine learning; Natural language processing; Reproducibility of results;
D O I
10.1186/s12911-021-01451-8
中图分类号
R-058 [];
学科分类号
摘要
Background With a motivation of quality assurance, machine learning techniques were trained to classify Norwegian radiology reports of paediatric CT examinations according to their description of abnormal findings. Methods 13.506 reports from CT-scans of children, 1000 reports from CT scan of adults and 1000 reports from X-ray examination of adults were classified as positive or negative by a radiologist, according to the presence of abnormal findings. Inter-rater reliability was evaluated by comparison with a clinician's classifications of 500 reports. Test-retest reliability of the radiologist was performed on the same 500 reports. A convolutional neural network model (CNN), a bidirectional recurrent neural network model (bi-LSTM) and a support vector machine model (SVM) were trained on a random selection of the children's data set. Models were evaluated on the remaining CT-children reports and the adult data sets. Results Test-retest reliability: Cohen's Kappa = 0.86 and F1 = 0.919. Inter-rater reliability: Kappa = 0.80 and F1 = 0.885. Model performances on the Children-CT data were as follows. CNN: (AUC = 0.981, F1 = 0.930), bi-LSTM: (AUC = 0.978, F1 = 0.927), SVM: (AUC = 0.975, F1 = 0.912). On the adult data sets, the models had AUC around 0.95 and F1 around 0.91. Conclusions The models performed close to perfectly on its defined domain, and also performed convincingly on reports pertaining to a different patient group and a different modality. The models were deemed suitable for classifying radiology reports for future quality assurance purposes, where the fraction of the examinations with abnormal findings for different sub-groups of patients is a parameter of interest.
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页数:8
相关论文
共 24 条
[1]  
[Anonymous], 2014, PROC C EMPIRICAL MET, DOI DOI 10.3115/V1/D14-1181
[2]   Document-level classification of CT pulmonary angiography reports based on an extension of the ConText algorithm [J].
Chapman, Brian E. ;
Lee, Sean ;
Kang, Hyunseok Peter ;
Chapman, Wendy W. .
JOURNAL OF BIOMEDICAL INFORMATICS, 2011, 44 (05) :728-737
[3]   Deep Learning to Classify Radiology Free-Text Reports [J].
Chen, Matthew C. ;
Ball, Robyn L. ;
Yang, Lingyao ;
Moradzadeh, Nathaniel ;
Chapman, Brian E. ;
Larson, David B. ;
Langlotz, Curtis P. ;
Amrhein, Timothy J. ;
Lungren, Matthew P. .
RADIOLOGY, 2018, 286 (03) :845-852
[4]   Extraction of recommendation features in radiology with natural language processing: Exploratory study [J].
Dang, Pragya A. ;
Kalra, Mannudeep K. ;
Blake, Michael A. ;
Schultz, Thomas J. ;
Halpern, Elkan F. ;
Dreyer, Keith J. .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2008, 191 (02) :313-320
[5]   What can natural language processing do for clinical decision support? [J].
Demner-Fushman, Dina ;
Chapman, Wendy W. ;
McDonald, Clement J. .
JOURNAL OF BIOMEDICAL INFORMATICS, 2009, 42 (05) :760-772
[6]  
Efron Bradley, 1994, An introduction to the bootstrap
[7]  
Elkin Peter L, 2008, AMIA Annu Symp Proc, P172
[8]   Automatic detection of acute bacterial pneumonia from chest x-ray reports [J].
Fiszman, M ;
Chapman, WW ;
Aronsky, D ;
Evans, RS ;
Haug, PJ .
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION, 2000, 7 (06) :593-604
[9]   A GENERAL NATURAL-LANGUAGE TEXT PROCESSOR FOR CLINICAL RADIOLOGY [J].
FRIEDMAN, C ;
ALDERSON, PO ;
AUSTIN, JHM ;
CIMINO, JJ ;
JOHNSON, SB .
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION, 1994, 1 (02) :161-174
[10]   Why and when to use CT in children: perspective of a pediatric emergency medicine physician [J].
Frush, Karen .
PEDIATRIC RADIOLOGY, 2014, 44 :409-413