The crystal structure of the 1:1 inclusion complex of β-cyclodextrin with benzamide

被引：31

作者：

Wang, En-Ju

Lian, Zhao-Xun

Cai, Jiwen ^{[1
]}

机构：

[1] Sun Yat Sen Univ, Sch Chem & Chem Engn, Guangzhou 510275, Peoples R China

[2] Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510080, Peoples R China

来源：

CARBOHYDRATE RESEARCH | 2007年 / 342卷 / 05期

关键词：

beta-cyclodextrin; benzamide; inclusion complex; crystal structure;

D O I：

10.1016/j.carres.2006.12.004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The 1:1 inclusion complex of P-cyclodextrin and benzamide was prepared and characterized by single crystal X-ray diffraction, PXRD, TGA, and IR. This complex crystallizes in the monoclinic P2(1) space group with unit cell constants a = 15.4244(16), b = 10.1574(11), c = 20.557(2) angstrom, beta = 110.074(2)degrees, V = 3025.1(6) angstrom(3). The guest molecule projects into the beta-cyclodextrin cavity from the primary hydroxyl side. The amide group protrudes from the primary hydroxyl side and forms hydrogen bonds with the adjacent beta-cyclodextrin molecule. There are six crystallized water molecules, which play crucial roles in crystal packing. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：767 / 771

页数：5

共 17 条

[1] Crystal structure of β-cyclodextrin-benzoic acid inclusion complex [J].