Although model protocellular membranes consisting of monoacyl lipids are similar to membranes composed of contemporary diacyl lipids, they differ in at least one important aspect. Model protocellular membranes allow for the passage of polar solutes and thus can potentially support cell-to functions without the aid of transport machinery. The ability to transport polar molecules likely stems from increased lipid dynamics. Selectively permeable vesicle membranes composed of monoacyl lipids allow for many lifelike processes to emerge from a remarkably small set of molecules.
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Carnegie Mellon Univ, Dept Phys, Biol Phys Grp, Pittsburgh, PA 15213 USA
Carnegie Mellon Univ, Dept Biol Sci, Pittsburgh, PA 15213 USACarnegie Mellon Univ, Dept Phys, Biol Phys Grp, Pittsburgh, PA 15213 USA
Nagle, John F.
Mathai, John C.
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Beth Israel Deaconess Med Ctr, Dept Med, Cambridge, MA 02139 USA
Harvard Univ, Sch Med, Cambridge, MA 02139 USACarnegie Mellon Univ, Dept Phys, Biol Phys Grp, Pittsburgh, PA 15213 USA
Mathai, John C.
Zeidel, Mark L.
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Beth Israel Deaconess Med Ctr, Dept Med, Cambridge, MA 02139 USA
Harvard Univ, Sch Med, Cambridge, MA 02139 USACarnegie Mellon Univ, Dept Phys, Biol Phys Grp, Pittsburgh, PA 15213 USA
Zeidel, Mark L.
Tristram-Nagle, Stephanie
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Carnegie Mellon Univ, Dept Phys, Biol Phys Grp, Pittsburgh, PA 15213 USACarnegie Mellon Univ, Dept Phys, Biol Phys Grp, Pittsburgh, PA 15213 USA
机构:
Carnegie Mellon Univ, Dept Phys, Biol Phys Grp, Pittsburgh, PA 15213 USA
Carnegie Mellon Univ, Dept Biol Sci, Pittsburgh, PA 15213 USACarnegie Mellon Univ, Dept Phys, Biol Phys Grp, Pittsburgh, PA 15213 USA
Nagle, John F.
Mathai, John C.
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机构:
Beth Israel Deaconess Med Ctr, Dept Med, Cambridge, MA 02139 USA
Harvard Univ, Sch Med, Cambridge, MA 02139 USACarnegie Mellon Univ, Dept Phys, Biol Phys Grp, Pittsburgh, PA 15213 USA
Mathai, John C.
Zeidel, Mark L.
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h-index: 0
机构:
Beth Israel Deaconess Med Ctr, Dept Med, Cambridge, MA 02139 USA
Harvard Univ, Sch Med, Cambridge, MA 02139 USACarnegie Mellon Univ, Dept Phys, Biol Phys Grp, Pittsburgh, PA 15213 USA
Zeidel, Mark L.
Tristram-Nagle, Stephanie
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h-index: 0
机构:
Carnegie Mellon Univ, Dept Phys, Biol Phys Grp, Pittsburgh, PA 15213 USACarnegie Mellon Univ, Dept Phys, Biol Phys Grp, Pittsburgh, PA 15213 USA