Immunotherapy: past, present and future

被引：441
作者：
Waldmann, TA [1 ]
机构：
[1] NCI, Metab Branch, Ctr Canc Res, NIH, Bethesda, MD 20892 USA
来源：
NATURE MEDICINE | 2003年 / 9卷 / 03期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1038/nm0303-269
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Harnessing the immune system to treat chronic infectious diseases or cancer is a major goal of immunotherapy. Among others, impediments to this aim include host failure to identify tumor antigens, tolerance to self and negative immunoregulatory mechanisms. But with recent progress, active and passive immunotherapy are proving themselves as effective therapeutic strategies.
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页码：269 / 277
页数：9
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