Post-Infectious Bronchiolitis Obliterans: Can CT Scan Findings at Early Age Anticipate Lung Function?

被引：28

作者：

Mattiello, Rita ^{[1
,2
]}

Sarria, Edgar E. ^{[1
,3
]}

Mallol, Javier ^{[3
]}

Fischer, Gilberto B. ^{[1
,4
]}

Mocelin, Helena ^{[1
]}

Bello, Rodrigo ^{[5
]}

Flores, Jose A. M. ^{[5
]}

Irion, Klaus ^{[6
,7
]}

Jones, Yvonne ^{[6
]}

机构：

[1] Hosp Crianca Santo Antonio, Pediat Pulmonol Sect, BR-90035074 Porto Alegre, RS, Brazil

[2] Univ Fed Rio Grande do Sul, Postgrad Program Pediat, Porto Alegre, RS, Brazil

[3] Univ Santiago Chile, Dept Pediat Resp Med, Hosp CRS El Pino, Santiago, RM, Chile

[4] Univ Fed Ciencias Saude Porto Alegre, Dept Pediat, Porto Alegre, RS, Brazil

[5] Hosp Crianca Santo Antonio, Dept Radiol, Porto Alegre, RS, Brazil

[6] Liverpool Heart & Chest Hosp, Dept Radiol, Liverpool, Merseyside, England

[7] Royal Liverpool Univ Hosp, Dept Radiol, Liverpool, Merseyside, England

来源：

PEDIATRIC PULMONOLOGY | 2010年 / 45卷 / 04期

关键词：

child; bronchiolitis obliterans; tomography; X-ray computed; respiratory function test; THIN-SECTION CT; RESOLUTION COMPUTED-TOMOGRAPHY; CYSTIC-FIBROSIS; CHILDREN; TRANSPLANTATION; STANDARDIZATION; EXERCISE; CAPACITY;

D O I：

10.1002/ppul.21115

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Background: The image findings of post-infectious bronchiolitis obliterans (PIBO) have been described, however, we do not know if such findings can predict lung function (LF) deterioration with increasing patient age. Aim: To assess whether computed tomography (CT) abnormalities detected at an early stage of the disease can anticipate abnormal LF a decade later in children with PIBO. Methods: We compared CT scans of 21 children with PIBO, done within their first 3 years of life, and their actual LE To evaluate CT scans we used a modified Bhalla score and, for LF, FEV1 as percentage of predicted values. We calculated prevalence ratios (PRs) by comparing the proportion of patients with worst CT score and worst LF, with the proportion of those with best CT score and worst LE Results: PR was 1.17 (CI 1.02; 1.34, P = 0.02). Conclusions: The CT finding early in the life of children with PIBO, when assessed by the Bhalla, score seem to anticipate future LF status. Pediatr Pulmonol. 2010; 45:315-319. (C) 2010 Wiley-Liss, Inc.

引用

页码：315 / 319

页数：5

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