Determination of Zilpaterol in Livestock Products by LC-MS/MS

被引：0

作者：

Asakura, Takayuki ^{[1
]}

Kitamura, Mariko ^{[1
]}

Ishikawa, Takaaki ^{[1
]}

Iida, Tomonari ^{[1
]}

Nakazato, Mitsuo ^{[1
]}

Yasuda, Kazuo ^{[1
]}

Nemoto, Satoru ^{[2
]}

机构：

[1] Inc Fdn Tokyo Kenbikyo In, Inst Food & Environm Sci, Chuo Ku, 5-1 Toyomi Cho, Tokyo 1040055, Japan

[2] Natl Inst Hlth Sci, Kawasaki Ku, 3-25-26 Tonomachi, Kawasaki, Kanagawa 2109501, Japan

来源：

FOOD HYGIENE AND SAFETY SCIENCE | 2019年 / 60卷 / 05期

关键词：

zilpaterol; beta(2)-agonist; livestock; LC-MS/MS; MASS; URINE; ASSAY;

D O I：

暂无

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

An analytical method for the determination of zilpaterol in livestock products was developed. The sample was stirred with n-hexane and n-hexane saturated acetonitrile, and zilpaterol in the sample was extracted with acetonitrile. The extract was cleaned up on a ODS cartridge column (1 g) and SCX cartridge column (500 mg). The LC separation was carried out using an Inertsil ODS-4 column and linear gradient elution with 0.1%formic acid and acetonitrile containing 0.1% formic acid as mobile phase. Detection of MS was carried out positive ion electrospray ionization mode. Average recoveries (n = 5) of zilpaterol from 6 kinds of livestock products fortified at the MRLs (0.01 mg/kg) were 87.0-99.4%, and the relative standard deviations were 2.4-6.3%. The limits of quantitation were 0.01 mg/kg.

引用

页码：127 / 133

页数：7

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