Emerging Droplet Microfluidics

被引：1202

作者：

Shang, Luoran ^{[1
]}

Cheng, Yao ^{[1
]}

Zhao, Yuanjin ^{[1
]}

机构：

[1] Southeast Univ, Sch Biol Sci & Med Engn, State Key Lab Bioelect, Nanjing 210096, Jiangsu, Peoples R China

来源：

CHEMICAL REVIEWS | 2017年 / 117卷 / 12期

基金：

中国国家自然科学基金; 美国国家科学基金会;

关键词：

ON-A-CHIP; MONODISPERSE DOUBLE EMULSIONS; CHOLESTERIC LIQUID-CRYSTALS; RAMAN-SPECTROSCOPY-CONCEPTS; HYDROGEL SUSPENSION ARRAY; POLYMERASE-CHAIN-REACTION; METAL-ORGANIC FRAMEWORKS; ORDER MULTIPLE EMULSIONS; INDUCED PHASE-SEPARATION; PROTEASE ACTIVITY ASSAY;

D O I：

10.1021/acs.chemrev.6b00848

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Droplet microfluidics generates and manipulates discrete droplets through immiscible multiphase flows inside microchannels. Due to its remarkable advantages, droplet microfluidics bears significant value in an extremely wide range of area.. In this review, we provide a comprehensive and in-depth insight into droplet microfluidics, covering fundamental research from microfluidic chip fabrication and droplet generation to the applications of droplets in bio(chemical) analysis and materials generation. The purpose of this review is to convey the fundamentals of droplet microfluidics, a critical analysis on its current status and challenges, and opinions on its future development. We believe this review will promote communications among biology, chemistry, physics, and materials science.

引用

页码：7964 / 8040

页数：77

共 544 条

[31] Physics and applications of microfluidics in biology [J].

Beebe, DJ ;

Mensing, GA ;

Walker, GM .

ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, 2002, 4 :261-286

[32] On-chip single-copy real-time reverse-transcription PCR in isolated picoliter droplets [J].

Beer, N. Reginald ;

Wheeler, Elizabeth K. ;

Lee-Houghton, Lorenna ;

Watkins, Nicholas ;

Nasarabadi, Shanavaz ;

Hebert, Nicole ;

Leung, Patrick ;

Arnold, Don W. ;

Bailey, Christopher G. ;

Colston, Bill W. .

ANALYTICAL CHEMISTRY, 2008, 80 (06) :1854-1858

[33]

Begolo S, 2011, LAB CHIP, V11, P508, DOI [10.1039/c0lc00356e, 10.1039/c01c00356e]

[34] High-throughput screening of filamentous fungi using nanoliter-range droplet-based microfluidics [J].

Beneyton, Thomas ;

Wijaya, I. Putu Mahendra ;

Postros, Prexilia ;

Najah, Majdi ;

Leblond, Pascal ;

Couvent, Angelique ;

Mayot, Estelle ;

Griffiths, Andrew D. ;

Drevelle, Antoine .

SCIENTIFIC REPORTS, 2016, 6

[35] Hydrogel bioprinted microchannel networks for vascularization of tissue engineering constructs [J].

Bertassoni, Luiz E. ;

Cecconi, Martina ;

Manoharan, Vijayan ;

Nikkhah, Mehdi ;

Hjortnaes, Jesper ;

Cristino, Ana Luiza ;

Barabaschi, Giada ;

Demarchi, Danilo ;

Dokmeci, Mehmet R. ;

Yang, Yunzhi ;

Khademhosseini, Ali .

LAB ON A CHIP, 2014, 14 (13) :2202-2211

[36]

Berthold A, 2002, ELECTROPHORESIS, V23, P3511, DOI 10.1002/1522-2683(200210)23:20<3511::AID-ELPS3511>3.0.CO

[37]

2-C

[38] Static micromixers based on large-scale industrial mixer geometry [J].

Bertsch, A ;

Heimgartner, S ;

Cousseau, P ;

Renaud, P .

LAB ON A CHIP, 2001, 1 (01) :56-60

[39] Discrete elements for 3D microfluidics [J].

Bhargava, Krisna C. ;

Thompson, Bryant ;

Malmstadt, Noah .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (42) :15013-15018

[40] A microfluidic droplet digital PCR for simultaneous detection of pathogenic Escherichia coli O157 and Listeria monocytogenes [J].

Bian, Xiaojun ;

Jing, Fengxiang ;

Li, Gang ;

Fan, Xiaoyun ;

Jia, Chunping ;

Zhou, Hongbo ;

Jin, Qinghui ;

Zhao, Jianlong .

BIOSENSORS & BIOELECTRONICS, 2015, 74 :770-777

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