Emerging Droplet Microfluidics

被引：1202
作者：
Shang, Luoran [1 ]
Cheng, Yao [1 ]
Zhao, Yuanjin [1 ]
机构：
[1] Southeast Univ, Sch Biol Sci & Med Engn, State Key Lab Bioelect, Nanjing 210096, Jiangsu, Peoples R China
来源：
CHEMICAL REVIEWS | 2017年 / 117卷 / 12期
基金：
中国国家自然科学基金; 美国国家科学基金会;
关键词：
ON-A-CHIP; MONODISPERSE DOUBLE EMULSIONS; CHOLESTERIC LIQUID-CRYSTALS; RAMAN-SPECTROSCOPY-CONCEPTS; HYDROGEL SUSPENSION ARRAY; POLYMERASE-CHAIN-REACTION; METAL-ORGANIC FRAMEWORKS; ORDER MULTIPLE EMULSIONS; INDUCED PHASE-SEPARATION; PROTEASE ACTIVITY ASSAY;
D O I：
10.1021/acs.chemrev.6b00848
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Droplet microfluidics generates and manipulates discrete droplets through immiscible multiphase flows inside microchannels. Due to its remarkable advantages, droplet microfluidics bears significant value in an extremely wide range of area.. In this review, we provide a comprehensive and in-depth insight into droplet microfluidics, covering fundamental research from microfluidic chip fabrication and droplet generation to the applications of droplets in bio(chemical) analysis and materials generation. The purpose of this review is to convey the fundamentals of droplet microfluidics, a critical analysis on its current status and challenges, and opinions on its future development. We believe this review will promote communications among biology, chemistry, physics, and materials science.
引用
收藏
页码：7964 / 8040
页数：77
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共 544 条
  • [91] Electrostatic potential wells for on-demand drop manipulation in microchannels
    de Ruiter, Rielle
    Pit, Arjen M.
    de Oliveira, Vitor Martins
    Duits, Michel H. G.
    van den Ende, Dirk
    Mugele, Frieder
    [J]. LAB ON A CHIP, 2014, 14 (05) : 883 - 891
  • [92] A Method for Detecting Circulating Tumor Cells Based on the Measurement of Single-Cell Metabolism in Droplet-Based Microfluidics
    Del Ben, Fabio
    Turetta, Matteo
    Celetti, Giorgia
    Piruska, Aigars
    Bulfoni, Michela
    Cesselli, Daniela
    Huck, Wilhelm T. S.
    Scoles, Giacinto
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 55 (30) : 8581 - 8584
  • [93] Control and detection of chemical reactions in microfluidic systems
    deMello, Andrew J.
    [J]. NATURE, 2006, 442 (7101) : 394 - 402
  • [94] The Synthesis and Assembly of Polymeric Microparticles Using Microfluidics
    Dendukuri, Dhananjay
    Doyle, Patrick S.
    [J]. ADVANCED MATERIALS, 2009, 21 (41) : 4071 - 4086
  • [95] Monodisperse Uni- and Multicompartment Liposomes
    Deng, Nan-Nan
    Yelleswarapu, Maaruthy
    Huck, Wilhelm T. S.
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2016, 138 (24) : 7584 - 7591
  • [96] Wetting-induced formation of controllable monodisperse multiple emulsions in microfluidics
    Deng, Nan-Nan
    Wang, Wei
    Ju, Xiao-Jie
    Xie, Rui
    Weitz, David A.
    Chu, Liang-Yin
    [J]. LAB ON A CHIP, 2013, 13 (20) : 4047 - 4052
  • [97] A novel surgery-like strategy for droplet coalescence in microchannels
    Deng, Nan-Nan
    Sun, Shao-Xing
    Wang, Wei
    Ju, Xiao-Jie
    Xie, Rui
    Chu, Liang-Yin
    [J]. LAB ON A CHIP, 2013, 13 (18) : 3653 - 3657
  • [98] Uniform Amplification of Phage with Different Growth Characteristics in Individual Compartments Consisting of Monodisperse Droplets
    Derda, Ratmir
    Tang, Sindy K. Y.
    Whitesides, George M.
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (31) : 5301 - 5304
  • [99] Octanol-assisted liposome assembly on chip
    Deshpande, Siddharth
    Caspi, Yaron
    Meijering, Anna E. C.
    Dekker, Cees
    [J]. NATURE COMMUNICATIONS, 2016, 7
  • [100] "V-junction": a novel structure for high-speed generation of bespoke droplet flows
    Ding, Yun
    Solvas, Xavier Casadevall i
    deMello, Andrew
    [J]. ANALYST, 2015, 140 (02) : 414 - 421
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