Emerging Droplet Microfluidics

被引:1202
作者
Shang, Luoran [1 ]
Cheng, Yao [1 ]
Zhao, Yuanjin [1 ]
机构
[1] Southeast Univ, Sch Biol Sci & Med Engn, State Key Lab Bioelect, Nanjing 210096, Jiangsu, Peoples R China
基金
中国国家自然科学基金; 美国国家科学基金会;
关键词
ON-A-CHIP; MONODISPERSE DOUBLE EMULSIONS; CHOLESTERIC LIQUID-CRYSTALS; RAMAN-SPECTROSCOPY-CONCEPTS; HYDROGEL SUSPENSION ARRAY; POLYMERASE-CHAIN-REACTION; METAL-ORGANIC FRAMEWORKS; ORDER MULTIPLE EMULSIONS; INDUCED PHASE-SEPARATION; PROTEASE ACTIVITY ASSAY;
D O I
10.1021/acs.chemrev.6b00848
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Droplet microfluidics generates and manipulates discrete droplets through immiscible multiphase flows inside microchannels. Due to its remarkable advantages, droplet microfluidics bears significant value in an extremely wide range of area.. In this review, we provide a comprehensive and in-depth insight into droplet microfluidics, covering fundamental research from microfluidic chip fabrication and droplet generation to the applications of droplets in bio(chemical) analysis and materials generation. The purpose of this review is to convey the fundamentals of droplet microfluidics, a critical analysis on its current status and challenges, and opinions on its future development. We believe this review will promote communications among biology, chemistry, physics, and materials science.
引用
收藏
页码:7964 / 8040
页数:77
相关论文
共 544 条
  • [1] High-Order Multiple Emulsions Formed in Poly(dimethylsiloxane) Microfluidics
    Abate, A. R.
    Weitz, D. A.
    [J]. SMALL, 2009, 5 (18) : 2030 - 2032
  • [2] High-throughput injection with microfluidics using picoinjectors
    Abate, Adam R.
    Hung, Tony
    Mary, Pascaline
    Agresti, Jeremy J.
    Weitz, David A.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (45) : 19163 - 19166
  • [3] Microfluidic sorting with high-speed single-layer membrane valves
    Abate, Adam R.
    Agresti, Jeremy J.
    Weitz, David A.
    [J]. APPLIED PHYSICS LETTERS, 2010, 96 (20)
  • [4] Microfluidic Fabrication of Stable Gas-Filled Microcapsules for Acoustic Contrast Enhancement
    Abbaspourrad, Alireza
    Duncanson, Wynter J.
    Lebedeva, Natalia
    Kim, Shin-Hyun
    Zhushma, Aleksandr P.
    Datta, Sujit S.
    Dayton, Paul A.
    Sheiko, Sergei S.
    Rubinstein, Michael
    Weitz, David A.
    [J]. LANGMUIR, 2013, 29 (40) : 12352 - 12357
  • [5] Polymer Microcapsules with Programmable Active Release
    Abbaspourrad, Alireza
    Carroll, Nick J.
    Kim, Shin-Hyun
    Weitz, David A.
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (20) : 7744 - 7750
  • [6] Lab-on-chip technologies:: making a microfluidic network and coupling it into a complete microsystem -: a review
    Abgrall, P.
    Gue, A-M
    [J]. JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 2007, 17 (05) : R15 - R49
  • [7] Enhancement of reaction rates by segmented fluid flow in capillary scale reactors
    Ahmed, Batoul
    Barrow, David
    Wirth, Thomas
    [J]. ADVANCED SYNTHESIS & CATALYSIS, 2006, 348 (09) : 1043 - 1048
  • [8] Dielectrophoretic manipulation of drops for high-speed microfluidic sorting devices
    Ahn, K
    Kerbage, C
    Hunt, TP
    Westervelt, RM
    Link, DR
    Weitz, DA
    [J]. APPLIED PHYSICS LETTERS, 2006, 88 (02) : 1 - 3
  • [9] Ameloot R, 2011, NAT CHEM, V3, P382, DOI [10.1038/NCHEM.1026, 10.1038/nchem.1026]
  • [10] Production of amorphous nanoparticles by supersonic spray-drying with a microfluidic nebulator
    Amstad, Esther
    Gopinadhan, Manesh
    Holtze, Christian
    Osuji, Chinedum O.
    Brenner, Michael P.
    Spaepen, Frans
    Weitz, David A.
    [J]. SCIENCE, 2015, 349 (6251) : 956 - 960