Elucidation of the elusive structure and formula of the active pharmaceutical ingredient bismuth subgallate by continuous rotation electron diffraction

被引：94

作者：

Wang, Yunchen ^{[1
]}

Takki, Sofia ^{[1
]}

Cheung, Ocean ^{[2
]}

Xu, Hongyi ^{[1
]}

Wan, Wei ^{[1
]}

Ohrstrom, Lars ^{[3
]}

Inge, A. Ken ^{[1
]}

机构：

[1] Stockholm Univ, Dept Mat & Environm Chem, S-10691 Stockholm, Sweden

[2] Heriot Watt Univ, Sch Engn & Phys Sci, Edinburgh EH14 4AS, Midlothian, Scotland

[3] Chalmers Univ Technol, Dept Chem & Chem Engn, S-41296 Gothenburg, Sweden

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 52期

基金：

瑞典研究理事会;

关键词：

METAL-ORGANIC FRAMEWORK; TOMOGRAPHY; IDENTIFICATION; ANTIMONY(III); SUBSALICYLATE; SUBCITRATE; COMPLEXES; THERAPY;

D O I：

10.1039/c7cc03180g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Bismuth subgallate has been used in wound and gastrointestinal therapy for over a century. The combination of continuous rotation electron diffraction and sample cooling finally revealed its structure as a coordination polymer. The structure provides insight regarding its formula, poor solubility, acid resistance and previously unreported gas sorption properties.

引用

页码：7018 / 7021

页数：4

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