The controversial role of TNF in melanoma

被引:19
作者
Donia, Marco [1 ,2 ]
Kjeldsen, Julie Westerlin [1 ]
Svane, Inge Marie [1 ,2 ]
机构
[1] Univ Copenhagen, Herlev Hosp, Dept Hematol, Ctr Canc Immune Therapy, DK-2730 Herlev, Denmark
[2] Univ Copenhagen, Herlev Hosp, Dept Oncol, DK-2730 Herlev, Denmark
关键词
Antitumor CD4 T cell responses; Melanoma; tumor immune escape; Tumor necrosis factor (TNF)- MHC class II; TUMOR-NECROSIS-FACTOR; CELL; METASTASIS;
D O I
10.1080/2162402X.2015.1107699
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
TNF has been associated with both inhibition and promotion of tumor growth. We recently described a mechanism by which tumor cells attract TNF producing cells via expression of MHC class II molecules.
引用
收藏
页数:2
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