Belgian guidelines for non-occupational HIV post-exposure prophylaxis 2017

被引:7
作者
Libois, Agnes [1 ]
Florence, Eric [2 ]
Derdelinckx, Inge [3 ]
Yombi, Jean Cyr [4 ]
Henrard, Sophie [5 ]
Uurlings, Francoise [6 ]
Vandecasteele, Stefaan [7 ]
Allard, Sabine D. [8 ]
Demeester, Remy [9 ]
Van Wanzeele, Filip [10 ]
Ausselet, Nathalie [11 ]
De Wit, Stephane [1 ]
机构
[1] ULB, CHU St Pierre, Dept Infect Dis, Brussels, Belgium
[2] Inst Trop Med, Antwerp, Belgium
[3] Univ Hosp Leuven, Dept Internal Med, Leuven, Belgium
[4] Clin Univ St Luc, Infect Dis & Trop Med Unit, Dept Internal Med, Brussels, Belgium
[5] Hop Erasme, Ctr Reference SIDA, Unite Traitements Immunodeficiences, Route Lennik 808, Brussels, Belgium
[6] Liege Univ Hosp, Infect Dis Dept, Liege, Belgium
[7] AZ Sint Jan Brugge, Dept Nephrol & Infect Dis, Brugge, Belgium
[8] Univ Ziekenhuis Brussel, Dept Internal Med & Infect Dis, Brussels, Belgium
[9] CHU Charleroi, Dept Internal Med & Infect Dis, Charleroi, Belgium
[10] Ghent Univ Hosp, Dept Gen Internal Med Infect Dis & Psychosomat, Ghent, Belgium
[11] CHU UCL Namur Godinne, Infect Dis Dept, Yvoir, Belgium
关键词
HIV; post-exposure prophylaxis; HUMAN-IMMUNODEFICIENCY-VIRUS; HEALTH-CARE WORKERS; HOMOSEXUAL-MEN; HETEROSEXUAL TRANSMISSION; INFECTION; RISK; EXPOSURE; SEROCONVERSION; PROBABILITY; PARTNERS;
D O I
10.1080/17843286.2018.1428506
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We present the updated Belgian guidelines for the use of non-occupational HIV post-exposure prophylaxis (NONOPEP). This document is inspired by UK guidelines 2015, adapted to the Belgian situation and approved by all AIDS reference centers in Belgium. When recommended, NONOPEP should be initiated as soon as possible, preferably within 24h of exposure but can be offered up to 72h. The duration of NONOPEP should be 28days. These current guidelines include epidemiologic estimations, which can be used to calculate the risk of infection after a potential exposure and help to decide whether or not to start prophylaxis. We review which medications to use in the context of the last Belgian NONOPEP convention, provide a checklist for initial assessment, and make recommendations for monitoring individuals receiving NONOPEP.
引用
收藏
页码:275 / 280
页数:6
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