Vitamin D Levels in Malnourished Children under 5 Years in a Tertiary Care Center at Muhimbili National Hospital, Dar es Salaam, Tanzania-A Cross-sectional Study

被引:17
作者
Walli, Nahida Z. [1 ]
Munubhi, Emmanuel K. [1 ]
Aboud, Said [2 ]
Manji, Karim P. [3 ]
机构
[1] Muhimbili Univ Hlth & Allied Sci, Dept Pediat & Child Hlth, Sch Med, Dar Es Salaam, Tanzania
[2] Muhimbili Univ Hlth & Allied Sci, Dept Microbiol & Immunol, Dar Es Salaam, Tanzania
[3] Muhimbili Univ Hlth & Allied Sci, Dept Pediat, Dar Es Salaam, Tanzania
关键词
vitamin D deficiency; malnourished children; Tanzania; DEVELOPING-COUNTRIES; MALNUTRITION; PREVALENCE; INFANTS; RICKETS;
D O I
10.1093/tropej/fmw081
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Objective: To evaluate vitamin D levels/deficiency among malnourished children <5 years admitted at a tertiary care center, the Muhimbili National Hospital, Dar es Salaam, Tanzania. Children with malnutrition may have co-existing vitamin D deficiency (VDD), which may be severe. Methods: Serum vitamin D and alkaline phosphatase were evaluated, and X-ray of the wrist was carried out on 134 children. Results: VDD was found in 41 of 134 children (30.6%). The mean vitamin D level was 74.8 nmol/l. The mean alkaline phosphatase level was 176.6U/l. Sixty-four (48%) children were found to have severe stunting, of whom 20 (31.2%) were vitamin D deficient. Marasmic children had higher odds of VDD compared with other forms of malnutrition. Conclusion: The high prevalence of VDD in malnourished children underlines the need for active surveillance and aggressive management.
引用
收藏
页码:203 / 209
页数:7
相关论文
共 25 条
  • [1] Vitamin D status and ill health: a systematic review
    Autier, Philippe
    Boniol, Mathieu
    Pizot, Cecile
    Mullie, Patrick
    [J]. LANCET DIABETES & ENDOCRINOLOGY, 2014, 2 (01) : 76 - 89
  • [2] Bener A, 2009, Minerva Pediatr, V61, P15
  • [3] Serum Vitamin D Levels and Markers of Severity of Childhood Asthma in Costa Rica
    Brehm, John M.
    Celedon, Juan C.
    Soto-Quiros, Manuel E.
    Avila, Lydiana
    Hunninghake, Gary M.
    Forno, Erick
    Laskey, Daniel
    Sylvia, Jody S.
    Hollis, Bruce W.
    Weiss, Scott T.
    Litonjua, Augusto A.
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2009, 179 (09) : 765 - 771
  • [4] Demographic, dietary, and biochemical determinants of vitamin D status in inner-city children
    Carpenter, Thomas O.
    Herreros, Francisca
    Zhang, Jane H.
    Ellis, Bruce K.
    Simpson, Christine
    Torrealba-Fox, Esther
    Kim, Grace J.
    Savoye, Mary
    Held, Nancy A.
    Cole, David E. C.
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 2012, 95 (01) : 137 - 146
  • [5] Caulfield LE, 2004, AM J CLIN NUTR, V80, P193
  • [6] Ejaz MS, 2010, J PAK MED ASSOC, V60, P543
  • [7] Postnatal malnutrition and growth retardation: An inevitable consequence of current recommendations in preterm infants?
    Embleton, NE
    Pang, N
    Cooke, RJ
    [J]. PEDIATRICS, 2001, 107 (02) : 270 - 273
  • [8] Prevalence of Vitamin D Insufficiency in Brazilian Adolescents
    Emo Peters, Barbara Santarosa
    dos Santos, Luana Caroline
    Fisberg, Mauro
    Wood, Richard James
    Martini, Ligia Araujo
    [J]. ANNALS OF NUTRITION AND METABOLISM, 2009, 54 (01) : 15 - 21
  • [9] Food And Agriculture Organization Of The United Nations, 2015, STAT FOOD INS WORLD
  • [10] Micronutrient Deficiencies and Related Factors in School-Aged Children in Ethiopia: A Cross-Sectional Study in Libo Kemkem and Fogera Districts, Amhara Regional State
    Herrador, Zaida
    Sordo, Luis
    Gadisa, Endalamaw
    Buno, Antonio
    Gomez-Rioja, Ruben
    Manuel Iturzaeta, Jose
    Fernandez de Armas, Lisset
    Benito, Agustin
    Aseffa, Abraham
    Moreno, Javier
    Canavate, Carmen
    Custodio, Estefania
    [J]. PLOS ONE, 2014, 9 (12):