GREENC: a Wiki-based database of plant lncRNAs

被引:155
作者
Paytuvi Gallart, Andreu [1 ]
Hermoso Pulido, Antonio [2 ,3 ]
Martinez de Lagran, Irantzu Anzar [1 ]
Sanseverino, Walter [1 ]
Aiese Cigliano, Riccardo [1 ]
机构
[1] Sequentia Biotech SL, Calle Comte DUrgell 240, Barcelona, Spain
[2] CRG, CRG Bioinformat Facil, Dr Aiguader 88, Barcelona 08003, Spain
[3] UPF, Dr Aiguader 88, Barcelona 08003, Spain
关键词
GENOME SEQUENCE; DRAFT GENOME; ANTISENSE TRANSCRIPTS; MESSENGER-RNA; EVOLUTION; INSIGHTS; REVEALS; PROVIDES; IDENTIFICATION; RESOURCE;
D O I
10.1093/nar/gkv1215
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Long non-coding RNAs (lncRNAs) are functional non-translated molecules greater than 200 nt. Their roles are diverse and they are usually involved in transcriptional regulation. LncRNAs still remain largely uninvestigated in plants with few exceptions. Experimentally validated plant lncRNAs have been shown to regulate important agronomic traits such as phosphate starvation response, flowering time and interaction with symbiotic organisms, making them of great interest in plant biology and in breeding. There is still a lack of lncRNAs in most sequenced plant species, and in those where they have been annotated, different methods have been used, so making the lncRNAs less useful in comparisons within and between species. We developed a pipeline to annotate lncRNAs and applied it to 37 plant species and six algae, resulting in the annotation of more than 120 000 lncRNAs. To facilitate the study of lncRNAs for the plant research community, the information gathered is organised in the Green Non-Coding Database (GreeNC, http: //greenc.sciencedesigners.com/).
引用
收藏
页码:D1161 / D1166
页数:6
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