Myocardial infarction with non-obstructive coronary artery (MINOCA): diagnostic framework, pathogenesis, therapy and prognosis

被引：9

作者：

Buono, Andrea ^{[1
]}

Pedrotti, Patrizia ^{[1
]}

Soriano, Francesco ^{[1
]}

Veas, Nicolas ^{[1
,2
]}

Oliva, Fabrizio ^{[1
]}

Oreglia, Jacopo ^{[1
]}

Ammirati, Enrico ^{[1
]}

机构：

[1] Azienda Socio Sanitaria Territoriale Grande Osped, Gasperis Cardio Ctr, Milan, Italy

[2] Clin Univ Los Andes, Santiago, Chile

来源：

GIORNALE ITALIANO DI CARDIOLOGIA | 2019年 / 20卷 / 09期

关键词：

MINOCA; Myocardial infarction with non-obstructive coronary arteries; Myocarditis; Takotsubo syndrome; Thromboembolism; CARDIOVASCULAR MAGNETIC-RESONANCE; ST-SEGMENT ELEVATION; LONG-TERM PROGNOSIS; FACTOR-V-LEIDEN; CHEST-PAIN; CLINICAL-FEATURES; INTRAVASCULAR ULTRASOUND; RISK STRATIFICATION; COAGULATION DEFECTS; GENDER-DIFFERENCES;

D O I：

10.1714/3207.31839

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The term MINOCA (myocardial infarction with non-obstructive coronary arteries) defines acute myocardial infarction with angiographic evidence of no significant coronary artery stenosis. Heterogeneous diseases are labelled as MINOCA. Incidence and epidemiological aspects differ on the basis of etiological causes. MINOCA include plaque (causing <50% stenosis) rupture or erosion, coronary embolism and dissection, and coronary artery spasm. Diagnosis may require multiple diagnostic tools, including cardiac imaging or provocative tests, in addition to standard coronary angiography, according to clinical suspicion. Cardiac magnetic resonance plays a key role in confirming the diagnosis and excluding other diseases with similar clinical presentation. Prognosis is not as benign as previously thought, on the opposite it is characterized by morbidity and mortality rates similar to other forms of myocardial infarction. Once the causative mechanism has been identified, appropriate therapy can be delivered.

引用

页码：499 / 511

页数：13

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