Case Report: Coinfection of Leishmania guyanensis and Human Immunodeficiency Virus-Acquired Immune Deficiency Syndrome: Report of a Case of Disseminated Cutaneous Leishmaniasis in Ecuador

被引：12

作者：

Calvopina, Manuel ^{[1
,6
]}

Aguirre, Cristina ^{[2
]}

Cevallos, William ^{[3
]}

Castillo, Alberto ^{[2
]}

Abbasi, Ibrahim ^{[4
]}

Warburg, Alon ^{[4
,5
]}

机构：

[1] UDLA, Carrera Med, Quito, Ecuador

[2] Hosp Eugenio Espejo, Serv Med Interna, Quito, Ecuador

[3] Univ Cent Ecuador, Carrera Med, Quito, Ecuador

[4] Hebrew Univ Jerusalem, Kuvin Ctr Study Infect & Trop Dis, Jerusalem, Israel

[5] Secretaria Nacl Educ Super Ciencia Tecnol & Innov, PROMETEO, Quito, Ecuador

[6] UDLA, Ave Granados E11-41 & Colimies,POB 17-17-9788, Quito, Ecuador

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2017年 / 96卷 / 05期

关键词：

TEGUMENTARY LEISHMANIASIS; NEW-WORLD; AIDS; EPIDEMIOLOGY; BRAZILIENSIS;

D O I：

10.4269/ajtmh.16-0431

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Reported herein is the first case of Leishmania-human immunodeficiency virus (HIV) coinfection in Ecuador. In Ecuador, HIV infections overlap endemic areas of leishmaniasis. Immunosuppression is a well-established risk factor for developing severe disease. This is a severe case of a 32-year-old man presenting with disseminated pleomorphic ulcers, papules, and cutaneous plaque-like lesions over his whole body. Numerous amastigotes were observed in both skin scrapings and biopsies. The sequence of the cytochrome b gene confirmed the presence of Leishmania guyanensis. The patient was treated but failed to respond to meglumine antimoniate and amphotericin B. Six months later, the patient died due to bacterial septic shock.

引用

页码：1151 / 1154

页数：4

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