Emergency Department Antimicrobial Considerations in Severe Sepsis

被引：6

作者：

Green, Robert S. ^{[1
,2
]}

Gorman, Sean K. ^{[3
]}

机构：

[1] Dalhousie Univ, Fac Med, Div Crit Care Med, Dept Anesthesia,Trauma Nova Scotia, Halifax, NS B3H 2Y9, Canada

[2] Dalhousie Univ, Fac Med, Dept Emergency Med, Trauma Nova Scotia, Halifax, NS B3H 2Y9, Canada

[3] Univ British Columbia, Fac Pharmaceut Sci, Interior Hlth Author, Serv Pharm, Kelowna, BC V1Y 3H5, Canada

来源：

EMERGENCY MEDICINE CLINICS OF NORTH AMERICA | 2014年 / 32卷 / 04期

关键词：

Severe sepsis; Emergency medicine; Timing of antimicrobials; Antimicrobial pharmacodynamics and pharmacokinetics; Procalcitonin; Antimicrobial shortages; CRITICALLY-ILL PATIENTS; CLINICAL-PRACTICE GUIDELINES; INTENSIVE-CARE PATIENTS; SURVIVING SEPSIS; ANTIBIOTIC-THERAPY; DRUG SHORTAGES; SEPTIC SHOCK; RISK-FACTORS; PROCALCITONIN; PHARMACOKINETICS;

D O I：

10.1016/j.emc.2014.07.014

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Severe sepsis and septic shock are common problems in the emergency department patient population and require expert clinical skill by members of the emergency department team to maximize optimal patient outcomes. Although various guidelines have been developed for the management of these patients, issues around antimicrobial-related considerations in critically ill patients require further evidence-based attention. In this review article, important factors related to patient illness, microorganism, timing of antimicrobial administration, and source control are discussed.

引用

页码：835 / +

页数：16

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