A functionalized gold nanoparticles-assisted universal carrier for antisense DNA

被引:48
作者
Kim, Jae-Hong [2 ]
Jang, Hyun Hye [3 ]
Ryou, Sang-Mi [1 ,2 ]
Kim, Sudeok [3 ]
Bae, Jeehyeon [2 ]
Lee, Kangseok [1 ]
Han, Min Su [3 ]
机构
[1] Chung Ang Univ, Dept Life Sci, Program BK21, Seoul 156756, South Korea
[2] CHA Univ, Grad Sch Life Sci & Biotechnol, Songnam 463836, South Korea
[3] Chung Ang Univ, Dept Chem, Seoul 156756, South Korea
基金
新加坡国家研究基金会;
关键词
GENE DELIVERY; CONTROLLED-RELEASE; MAMMALIAN-CELLS; DRUG-DELIVERY; THERAPY; VECTORS; THERAPEUTICS; TRANSFECTION; BIOLOGY; AGENTS;
D O I
10.1039/c0cc00103a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In this study, single-stranded DNA functionalized gold nanoparticles (AuNP GDS) were proved to be efficient gene delivery systems for oligo antisense DNAs specific to any gene of interest without affecting normal cell physiology.
引用
收藏
页码:4151 / 4153
页数:3
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