Disassembly of Dipeptide Single Crystals Can Transform the Lipid Membrane into a Network

被引：32
作者：
Fu, Meifang [1 ,3 ]
Li, Qi [1 ,3 ]
Sun, Bingbing [1 ,3 ]
Yang, Yang [2 ]
Dai, Luru [2 ]
Nylander, Tommy [4 ]
Li, Junbai [1 ,3 ]
机构：
[1] Chinese Acad Sci, Inst Chem, CAS Key Lab Colloid Interface & Thermodynam, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China
[2] Natl Ctr Nanosci & Technol, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China
[3] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
[4] Lund Univ, Dept Chem, Div Phys Chem, POB 124, SE-22100 Lund, Sweden
来源：
ACS NANO | 2017年 / 11卷 / 07期
基金：
中国国家自然科学基金;
关键词：
phospholipids; self-assembly; peptides; membranes; biomimetic; ASSEMBLED PEPTIDE NANOTUBES; CYTOSKELETON ADHESION; ENDOPLASMIC-RETICULUM; IN-VITRO; VESICLE; DIPHENYLALANINE; DYNAMICS; NANOSTRUCTURES; CONSTRUCTION; BIOLOGY;
D O I：
10.1021/acsnano.7b03468
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Coupling between cytoskeleton and membranes is critical to cell movement as well as organelle formation. Here, we demonstrate that self-assembled single crystals of a dipeptide, diphenylalanine (FF), can interact with liposomes to form cytoskeleton-like structures. Under a physiological condition, disassembly of FF crystals deforms and translocates supported lipid membrane. The system exhibits similar dynamic characteristics to the endoplasmic reticulum (ER) network in cells. This bottom-up system thus indicates that external matter can participate in the deformation of liposomes, and disassembly of the nanostructures enables a system with distinct dynamic behaviors.
引用
收藏
页码：7349 / 7354
页数：6
相关论文
共 37 条
  • [1] The physical properties of supramolecular peptide assemblies: from building block association to technological applications
    Adler-Abramovich, Lihi
    Gazit, Ehud
    [J]. CHEMICAL SOCIETY REVIEWS, 2014, 43 (20) : 6881 - 6893
  • [2] Stability of diphenylalanine peptide nanotubes in solution
    Andersen, Karsten Brandt
    Castillo-Leon, Jaime
    Hedstrom, Martin
    Svendsen, Winnie Edith
    [J]. NANOSCALE, 2011, 3 (03) : 994 - 998
  • [3] Nanoarchitectonics for Dynamic Functional Materials from Atomic-/Molecular-Level Manipulation to Macroscopic Action
    Ariga, Katsuhiko
    Li, Junbai
    Fei, Jinbo
    Ji, Qingmin
    Hill, Jonathan P.
    [J]. ADVANCED MATERIALS, 2016, 28 (06) : 1251 - 1286
  • [4] Supramolecular Differentiation for Construction of Anisotropic Fullerene Nanostructures by Time-Programmed Control of Interfacial Growth
    Bairi, Purtha
    Minami, Kosuke
    Hill, Jonathan P.
    Nakanishi, Waka
    Shrestha, Lok Kumar
    Liu, Chao
    Harano, Koji
    Nakamura, Eiichi
    Ariga, Katsuhiko
    [J]. ACS NANO, 2016, 10 (09) : 8796 - 8802
  • [5] Molecular phospholipid films on solid supports
    Czolkos, Ilja
    Jesorka, Aldo
    Orwar, Owe
    [J]. SOFT MATTER, 2011, 7 (10) : 4562 - 4576
  • [6] Fluid and Highly Curved Model Membranes on Vertical Nanowire Arrays
    Dabkowska, Aleksandra P.
    Niman, Cassandra S.
    Piret, Gaelle
    Persson, Henrik
    Wacklin, Hanna P.
    Linke, Heiner
    Prinz, Christelle N.
    Nylander, Tommy
    [J]. NANO LETTERS, 2014, 14 (08) : 4286 - 4292
  • [7] The structure of nanotubes formed by diphenylalanine, the core recognition motif of Alzheimer's β-amyloid polypeptide
    Goerbitz, Carl Henrik
    [J]. CHEMICAL COMMUNICATIONS, 2006, (22) : 2332 - 2334
  • [8] Connecting the Cytoskeleton to the Endoplasmic Reticulum and Golgi
    Gurel, Pinar S.
    Hatch, Anna L.
    Higgs, Henry N.
    [J]. CURRENT BIOLOGY, 2014, 24 (14) : R660 - R672
  • [9] Molecular assembly and application of biomimetic microcapsules
    He, Qiang
    Cui, Yue
    Li, Junbai
    [J]. CHEMICAL SOCIETY REVIEWS, 2009, 38 (08) : 2292 - 2303
  • [10] Generation of phospholipid vesicle-nanotube networks and transport of molecules therein
    Jesorka, Aldo
    Stepanyants, Natalia
    Zhang, Haijiang
    Ortmen, Bahanur
    Hakonen, Bodil
    Orwar, Owe
    [J]. NATURE PROTOCOLS, 2011, 6 (06) : 791 - 805
1234