Synthesis of 1,3,2-Benzodiazaphosphorine and 1,3,2-Benzodiazaphosphorine-2-sulfide

被引：1

作者：

Hichri, Sarra ^{[1
]}

Abderrahim, Raoudha ^{[1
]}

机构：

[1] Univ Carthage Tunisia, Fac Sci Bizerte, Dept Chem, Zarzouna 7021, Bizerte, Tunisia

来源：

LETTERS IN ORGANIC CHEMISTRY | 2016年 / 13卷 / 04期

关键词：

1,3,2-benzodiazaphosphorine; 1,3,2-benzodiazaphosphorine-2-sulfide; 2-amino-benzamidine; sulfur; tris (dimethyl amino) phosphine; DERIVATIVES; 2-OXIDES;

D O I：

10.2174/1570178613666160224005908

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Background: Benzodiazaphosphorines have many biological activities such as fungicidal and antitumor. In this work we are interested to synthesize them in order to test their activities in future work. The probable mechanism of obtained benzodiazaphosphorines is discussed. Methods: The obtained benzodiazaphosphorines were characterized using FT-IR, NMR H-1 and C-13 spectroscopy and elemental analysis. Results: A series of new benzodiazaphosphorines products synthesized were purified by crystallization and obtained with good yields. Conclusion: In this paper we have synthesized a series of benzodiazaphosphorine and benzodiazaphosphorine sulfide which are identified using FT-IR, NMR spectroscopy and elemental analysis. The prepared compounds will be subsequently studied in order to tested their biological activities.

引用

页码：289 / 292

页数：4

共 50 条

[21] 1,3,2-Diselenaborolanes with an Annelated Dicarba-closo-dodecaborane(12) Unit: Synthesis, Molecular Structure and Reactivity
Wrackmeyer, Bernd
Klimkina, Elena V.
Milius, Wolfgang
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2011, (28) : 4481 - 4492
[22] 2-{9-(10-Bromoanthracenyl)}-1,3-dihydro-1H-[d]-1,3,2-benzodiazaborole
Sithebe, Siphamandla
MOLBANK, 2023, 2023 (01)
[23] Synthesis and Bioactivity of Some New 3-Alkyl-2,4-diisopropyl-1,2,4,5-tetrahydro-benzo[e][1,3,2]-diazaphosphepine 3-sulfides/selenides
Mohan, Ch.
Raju, C. Naga
Rao, A. Janardhan
E-JOURNAL OF CHEMISTRY, 2008, 5 (03) : 479 - 486
[24] Reversible chair ⇆ skew conformational interconversion of 1,3,2-dioxaphosphorinane ring in the solid state
Slepokura, Katarzyna Anna
ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE CRYSTAL ENGINEERING AND MATERIALS, 2016, 72 : 117 - 125
[25] 1,3,2-Dithiaphospholanes with an annelated 1,2-dicarba-closo-dodecaborane(12) unit: formation and reactivity
Wrackmeyer, Bernd
Klimkina, Elena V.
Milius, Wolfgang
DALTON TRANSACTIONS, 2014, 43 (13) : 5021 - 5043
[26] Synthesis and photophysical properties of trichloro(fluoro)-Substituted 6-(3-oxo-1-(alk-1-en-1-yl)amino)coumarins and their 2,2-Difluoro-2H-1,3,2-oxazaborinin-3-ium-2-uide heterocycles
Rosa, Wilian C.
Rocha, Inaia O.
Schmitz, Bruna F.
Rodrigues, Melissa B.
Martins, Marcos A. P.
Zanatta, Nilo
Acunha, Thiago, V
Iglesias, Bernardo A.
Bonacorso, Helio G.
JOURNAL OF FLUORINE CHEMISTRY, 2020, 238
[27] Synthesis and characterisation of 3,4-dialkoxy-substituted benzo-1,3,2-dithiazolyl radicals
Alberola, Antonio
Eisler, Dana
Less, Robert J.
Navarro-Moratalla, Efren
Rawson, Jeremy M.
CHEMICAL COMMUNICATIONS, 2010, 46 (33) : 6114 - 6116
[28] Trimethylchlorosilane-Catalyzed Intramolecular Cyclization of 2-(2-Benzylideneaminoethyloxy)-1-phenylbenzo[e]-1,3,2-azaoxaphosphorin-4-one
Dimukhametov, M. N.
Ivkova, G. A.
Khayarov, Kh. R.
Musin, R. Z.
Mironov, V. F.
RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2018, 88 (09) : 1938 - 1940
[29] Synthesis and Conformational Preferences of Novel Steroidal 16-Spiro-1,3,2-Dioxaphosphorinanes
Frank, Eva
Sipos, Laszlo
Woelfling, Janos
Schneider, Gyula
LETTERS IN ORGANIC CHEMISTRY, 2009, 6 (04) : 340 - 344
[30] Synthesis, Antibacterial and Anticancer Activity of 1,2-Substituted 2,3-Dihydro-1H-Benzo[4,5]Imidazo[1,2-c][1,3,2]Diazaphosphol-1-Oxides
Sankar, V.
Cheeran, Vinnie
Ganesh, M. R.
Sivakumar, B.
PHARMACEUTICAL CHEMISTRY JOURNAL, 2020, 54 (08) : 827 - 833

← 1 2 3 4 5 →