Synthesis of 1,3,2-Benzodiazaphosphorine and 1,3,2-Benzodiazaphosphorine-2-sulfide

被引：1
作者：
Hichri, Sarra [1 ]
Abderrahim, Raoudha [1 ]
机构：
[1] Univ Carthage Tunisia, Fac Sci Bizerte, Dept Chem, Zarzouna 7021, Bizerte, Tunisia
来源：
LETTERS IN ORGANIC CHEMISTRY | 2016年 / 13卷 / 04期
关键词：
1,3,2-benzodiazaphosphorine; 1,3,2-benzodiazaphosphorine-2-sulfide; 2-amino-benzamidine; sulfur; tris (dimethyl amino) phosphine; DERIVATIVES; 2-OXIDES;
D O I：
10.2174/1570178613666160224005908
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Background: Benzodiazaphosphorines have many biological activities such as fungicidal and antitumor. In this work we are interested to synthesize them in order to test their activities in future work. The probable mechanism of obtained benzodiazaphosphorines is discussed. Methods: The obtained benzodiazaphosphorines were characterized using FT-IR, NMR H-1 and C-13 spectroscopy and elemental analysis. Results: A series of new benzodiazaphosphorines products synthesized were purified by crystallization and obtained with good yields. Conclusion: In this paper we have synthesized a series of benzodiazaphosphorine and benzodiazaphosphorine sulfide which are identified using FT-IR, NMR spectroscopy and elemental analysis. The prepared compounds will be subsequently studied in order to tested their biological activities.
引用
收藏
页码：289 / 292
页数：4
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